Cargando…

In Silico Drug Design for Purinergic GPCRs: Overview on Molecular Dynamics Applied to Adenosine and P2Y Receptors

Molecular modeling has contributed to drug discovery for purinergic GPCRs, including adenosine receptors (ARs) and P2Y receptors (P2YRs). Experimental structures and homology modeling have proven to be useful in understanding and predicting structure activity relationships (SAR) of agonists and anta...

Descripción completa

Detalles Bibliográficos
Autores principales: Salmaso, Veronica, Jacobson, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356333/
https://www.ncbi.nlm.nih.gov/pubmed/32466404
http://dx.doi.org/10.3390/biom10060812

Ejemplares similares