Cargando…

Impact of HPMCAS on the Dissolution Performance of Polyvinyl Alcohol Celecoxib Amorphous Solid Dispersions

Amorphous solid dispersions (ASDs) have been proven to increase the bioavailability of poorly soluble drugs. It is desirable that the ASD provide a rapid dissolution rate and a sufficient stabilization of the generated supersaturation. In many cases, one polymer alone is not able to provide both fea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Monschke, Marius, Wagner, Karl G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356348/ https://www.ncbi.nlm.nih.gov/pubmed/32545270 http://dx.doi.org/10.3390/pharmaceutics12060541

Ejemplares similares

Processing of Polyvinyl Acetate Phthalate in Hot-Melt Extrusion—Preparation of Amorphous Solid Dispersions
por: Monschke, Marius, et al.
Publicado: (2020)

Dissolution-permeation of hot-melt extruded amorphous solid dispersion comprising an experimental grade of HPMCAS
por: Tanaka, Hironori, et al.
Publicado: (2023)

Preparation and Characterization of Aprepitant Solid Dispersion with HPMCAS-LF
por: Liu, Jinwen, et al.
Publicado: (2022)

Influence of solvent mixtures on HPMCAS-celecoxib microparticles prepared by electrospraying
por: Bohr, Adam, et al.
Publicado: (2018)

Influence of Particle Size and Drug Load on Amorphous Solid Dispersions Containing pH-Dependent Soluble Polymers and the Weak Base Ketoconazole
por: Monschke, Marius, et al.
Publicado: (2021)

Downstream Processing of Itraconazole:HPMCAS Amorphous Solid Dispersion: From Hot-Melt Extrudate to Tablet Using a Quality by Design Approach
por: Mishra, Saurabh M, et al.
Publicado: (2022)

HPMCAS-Based Amorphous Solid Dispersions in Clinic: A Review on Manufacturing Techniques (Hot Melt Extrusion and Spray Drying), Marketed Products and Patents
por: Corrie, Leander, et al.
Publicado: (2023)

Oral Delivery of Niclosamide as an Amorphous Solid Dispersion That Generates Amorphous Nanoparticles during Dissolution
por: Jara, Miguel O., et al.
Publicado: (2022)

Investigating the Dissolution Performance of Amorphous Solid Dispersions Using Magnetic Resonance Imaging and Proton NMR
por: Tres, Francesco, et al.
Publicado: (2015)

Nanoseeded Desupersaturation and Dissolution Tests for Elucidating Supersaturation Maintenance in Amorphous Solid Dispersions
por: Guner, Gulenay, et al.
Publicado: (2023)

Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?
por: Neuwirth, Marius, et al.
Publicado: (2023)

Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol(®) Enabled Amorphous Solid Dispersions
por: Gala, Urvi, et al.
Publicado: (2020)

Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions
por: Pöstges, Florian, et al.
Publicado: (2022)

A Rational Design of a Biphasic Dissolution Setup—Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion
por: Denninger, Alexander, et al.
Publicado: (2020)

Orally Disintegrating Tablets Containing Melt Extruded Amorphous Solid Dispersion of Tacrolimus for Dissolution Enhancement
por: Ponnammal, Poovizhi, et al.
Publicado: (2018)

Physical Stability and Dissolution of Lumefantrine Amorphous Solid Dispersions Produced by Spray Anti-Solvent Precipitation
por: Bhujbal, Sonal V., et al.
Publicado: (2021)

Co-amorphous solid dispersion systems of lacidipine-spironolactone with improved dissolution rate and enhanced physical stability
por: Wang, Zhaomeng, et al.
Publicado: (2019)

Amorphous Solid Dispersions and the Contribution of Nanoparticles to In Vitro Dissolution and In Vivo Testing: Niclosamide as a Case Study
por: Jara, Miguel O., et al.
Publicado: (2021)

Comparison of Amorphous Solid Dispersions of Spironolactone Prepared by Spray Drying and Electrospinning: The Influence of the Preparation Method on the Dissolution Properties
por: Szabó, Edina, et al.
Publicado: (2020)

Effect of Drug–Polymer Interaction in Amorphous Solid Dispersion on the Physical Stability and Dissolution of Drugs: The Case of Alpha-Mangostin
por: Budiman, Arif, et al.
Publicado: (2023)

Artemether-Soluplus Hot-Melt Extrudate Solid Dispersion Systems for Solubility and Dissolution Rate Enhancement with Amorphous State Characteristics
por: Fule, Ritesh A., et al.
Publicado: (2013)

Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids from Selaginella doederleinii extract by amorphous solid dispersion
por: Chen, Bing, et al.
Publicado: (2020)

How Does the Addition of Kollidon(®)VA64 Inhibit the Recrystallization and Improve Ezetimibe Dissolution from Amorphous Solid Dispersions?
por: Szafraniec-Szczęsny, Joanna, et al.
Publicado: (2021)

Development of spray-dried amorphous solid dispersions of tadalafil using glycyrrhizin for enhanced dissolution and aphrodisiac activity in male rats
por: Muqtader Ahmed, Mohammed, et al.
Publicado: (2020)

Amorphous solid dispersion preparation via coprecipitation improves the dissolution, oral bioavailability, and intestinal health enhancement properties of magnolol
por: Cao, Jia, et al.
Publicado: (2023)

Enhancement of Aqueous Solubility and Dissolution of Celecoxib through Phosphatidylcholine-Based Dispersion Systems Solidified with Adsorbent Carriers
por: Jo, Kanghee, et al.
Publicado: (2018)

Thermal Stability of Amorphous Solid Dispersions
por: Jelić, Dijana
Publicado: (2021)

Enhancement of dissolution of Telmisartan through use of solid dispersion technique - surface solid dispersion
por: Patel, Bhumika, et al.
Publicado: (2012)

Investigation of Dissolution Mechanism and Release Kinetics of Poorly Water-Soluble Tadalafil from Amorphous Solid Dispersions Prepared by Various Methods
por: Školáková, Tereza, et al.
Publicado: (2019)

The inhibiting role of hydroxypropylmethylcellulose acetate succinate on piperine crystallization to enhance its dissolution from its amorphous solid dispersion and permeability
por: Deng, Yueyi, et al.
Publicado: (2019)

In vitro Dissolution Studies on Solid Dispersions of Mefenamic Acid
por: Rao, K. R. S. Sambasiva, et al.
Publicado: (2011)

Dissolution enhancement of efavirenz by solid dispersion and PEGylation techniques
por: Madhavi, B. Bindu, et al.
Publicado: (2011)

In vitro dissolution study of atorvastatin binary solid dispersion
por: Jahan, Rahat, et al.
Publicado: (2013)

Thermodynamics of dissolution and infrared-spectroscopy of solid dispersions of phenacetin
por: Gerasimov, Alexander V., et al.
Publicado: (2016)

Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying
por: Schönfeld, Barbara V., et al.
Publicado: (2021)

Cellulose based polymers in development of amorphous solid dispersions
por: Chavan, Rahul B, et al.
Publicado: (2019)

Synthesis and Electrical Percolation of Highly Amorphous Polyvinyl Alcohol/Reduced Graphene Oxide Nanocomposite
por: Adami, Renata, et al.
Publicado: (2023)

Mechanism and Improved Dissolution of Glycyrrhetinic Acid Solid Dispersion by Alkalizers
por: Dong, Luning, et al.
Publicado: (2020)

Preparation and Characterization of Amorphous Solid Dispersions for the Solubilization of Fenretinide
por: Zuccari, Guendalina, et al.
Publicado: (2023)

Amorphous Solid Dispersion as Drug Delivery Vehicles in Cancer
por: Budiman, Arif, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2ap4s91a2am09rkrvsdn26jblr