Cargando…

Estimating the Risk of COVID-19 Death during the Course of the Outbreak in Korea, February–May 2020

Background: In Korea, a total of 10,840 confirmed cases of COVID-19 including 256 deaths have been recorded as of May 9, 2020. The time-delay adjusted case fatality risk (CFR) of COVID-19 in Korea is yet to be estimated. Methods: We obtained the daily series of confirmed cases and deaths in Korea re...

Descripción completa

Detalles Bibliográficos
Autores principales: Shim, Eunha, Mizumoto, Kenji, Choi, Wongyeong, Chowell, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356403/
https://www.ncbi.nlm.nih.gov/pubmed/32485871
http://dx.doi.org/10.3390/jcm9061641
_version_ 1783558490831192064
author Shim, Eunha
Mizumoto, Kenji
Choi, Wongyeong
Chowell, Gerardo
author_facet Shim, Eunha
Mizumoto, Kenji
Choi, Wongyeong
Chowell, Gerardo
author_sort Shim, Eunha
collection PubMed
description Background: In Korea, a total of 10,840 confirmed cases of COVID-19 including 256 deaths have been recorded as of May 9, 2020. The time-delay adjusted case fatality risk (CFR) of COVID-19 in Korea is yet to be estimated. Methods: We obtained the daily series of confirmed cases and deaths in Korea reported prior to May 9, 2020. Using statistical methods, we estimated the time-delay adjusted risk for death from COVID-19 in Daegu, Gyeongsangbuk-do, other regions in Korea, as well as the entire country. Results: Our model-based crude CFR fitted the observed data well throughout the course of the epidemic except for the very early stage in Gyeongsangbuk-do; this was partially due to the reporting delay. Our estimates of the risk of death in Gyeongsangbuk-do reached 25.9% (95% Credible Interval (CrI): 19.6%–33.6%), 20.8% (95% CrI: 18.1%–24.0%) in Daegu, and 1.7% (95% CrI: 1.1%–2.5%) in other regions, whereas the national estimate was 10.2% (95% CrI: 9.0%–11.5%). Conclusions: The latest estimates of CFR of COVID-19 in Korea are considerably high, even with the early implementation of public health interventions including widespread testing, social distancing, and delayed school openings. Geographic differences in the CFR are likely influenced by clusters tied to hospitals and nursing homes.
format Online
Article
Text
id pubmed-7356403
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-73564032020-07-30 Estimating the Risk of COVID-19 Death during the Course of the Outbreak in Korea, February–May 2020 Shim, Eunha Mizumoto, Kenji Choi, Wongyeong Chowell, Gerardo J Clin Med Article Background: In Korea, a total of 10,840 confirmed cases of COVID-19 including 256 deaths have been recorded as of May 9, 2020. The time-delay adjusted case fatality risk (CFR) of COVID-19 in Korea is yet to be estimated. Methods: We obtained the daily series of confirmed cases and deaths in Korea reported prior to May 9, 2020. Using statistical methods, we estimated the time-delay adjusted risk for death from COVID-19 in Daegu, Gyeongsangbuk-do, other regions in Korea, as well as the entire country. Results: Our model-based crude CFR fitted the observed data well throughout the course of the epidemic except for the very early stage in Gyeongsangbuk-do; this was partially due to the reporting delay. Our estimates of the risk of death in Gyeongsangbuk-do reached 25.9% (95% Credible Interval (CrI): 19.6%–33.6%), 20.8% (95% CrI: 18.1%–24.0%) in Daegu, and 1.7% (95% CrI: 1.1%–2.5%) in other regions, whereas the national estimate was 10.2% (95% CrI: 9.0%–11.5%). Conclusions: The latest estimates of CFR of COVID-19 in Korea are considerably high, even with the early implementation of public health interventions including widespread testing, social distancing, and delayed school openings. Geographic differences in the CFR are likely influenced by clusters tied to hospitals and nursing homes. MDPI 2020-05-29 /pmc/articles/PMC7356403/ /pubmed/32485871 http://dx.doi.org/10.3390/jcm9061641 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Shim, Eunha
Mizumoto, Kenji
Choi, Wongyeong
Chowell, Gerardo
Estimating the Risk of COVID-19 Death during the Course of the Outbreak in Korea, February–May 2020
title Estimating the Risk of COVID-19 Death during the Course of the Outbreak in Korea, February–May 2020
title_full Estimating the Risk of COVID-19 Death during the Course of the Outbreak in Korea, February–May 2020
title_fullStr Estimating the Risk of COVID-19 Death during the Course of the Outbreak in Korea, February–May 2020
title_full_unstemmed Estimating the Risk of COVID-19 Death during the Course of the Outbreak in Korea, February–May 2020
title_short Estimating the Risk of COVID-19 Death during the Course of the Outbreak in Korea, February–May 2020
title_sort estimating the risk of covid-19 death during the course of the outbreak in korea, february–may 2020
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356403/
https://www.ncbi.nlm.nih.gov/pubmed/32485871
http://dx.doi.org/10.3390/jcm9061641
work_keys_str_mv AT shimeunha estimatingtheriskofcovid19deathduringthecourseoftheoutbreakinkoreafebruarymay2020
AT mizumotokenji estimatingtheriskofcovid19deathduringthecourseoftheoutbreakinkoreafebruarymay2020
AT choiwongyeong estimatingtheriskofcovid19deathduringthecourseoftheoutbreakinkoreafebruarymay2020
AT chowellgerardo estimatingtheriskofcovid19deathduringthecourseoftheoutbreakinkoreafebruarymay2020