Tumoricidal Potential of Novel Amino-1,10-phenanthroline Derived Imine Ligands: Chemical Preparation, Structure, and Biological Investigations

Herein we report the synthesis and structural elucidation of two novel imine-based ligands, 2-(1,10-phenanthrolin-5-yl)imino)methyl)-5-bromophenol (PIB) and N-(1,10-phenanthrolin-5-yl)-1-(thiophen-3-yl)methanimine (PTM) ligands. An in vitro cytotoxicity assay of the synthesized molecules was carried...

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Detalles Bibliográficos
Autores principales: Prasad, Kollur Shiva, Pillai, Renjith Raveendran, Shivamallu, Chandan, Prasad, Shashanka K., Jain, Anisha S., Pradeep, Sushma, Armaković, Stevan, Armaković, Sanja J., Srinivasa, Chandrashekar, Kallimani, Sharadadevi, Amachawadi, Raghavendra G., Ankegowda, Veena Malligere, Marraiki, Najat, Elgorban, Abdallah M., Syed, Asad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356530/
https://www.ncbi.nlm.nih.gov/pubmed/32580359
http://dx.doi.org/10.3390/molecules25122865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356530/
https://www.ncbi.nlm.nih.gov/pubmed/32580359
http://dx.doi.org/10.3390/molecules25122865

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