Role of Rutin in 5-Fluorouracil-Induced Intestinal Mucositis: Prevention of Histological Damage and Reduction of Inflammation and Oxidative Stress

Intestinal mucositis, characterized by inflammatory and/or ulcerative processes in the gastrointestinal tract, occurs due to cellular and tissue damage following treatment with 5-fluorouracil (5-FU). Rutin (RUT), a natural flavonoid extracted from Dimorphandra gardneriana, exhibits antioxidant, anti...

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Detalles Bibliográficos
Autores principales: Fideles, Lázaro de Sousa, de Miranda, João Antônio Leal, Martins, Conceição da Silva, Barbosa, Maria Lucianny Lima, Pimenta, Helder Bindá, Pimentel, Paulo Vitor de Souza, Teixeira, Claudio Silva, Scafuri, Marina Alves Sampaio, Façanha, Samuel de Osterno, Barreto, João Erivan Façanha, Carvalho, Poliana Moreira de Medeiros, Scafuri, Ariel Gustavo, Araújo, Joabe Lima, Rocha, Jefferson Almeida, Vieira, Icaro Gusmão Pinto, Ricardo, Nágila Maria Pontes Silva, da Silva Campelo, Matheus, Ribeiro, Maria Elenir Nobre Pinho, de Castro Brito, Gerly Anne, Cerqueira, Gilberto Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356626/
https://www.ncbi.nlm.nih.gov/pubmed/32560278
http://dx.doi.org/10.3390/molecules25122786

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