Cationic Dendrimer G2-S16 Inhibits Herpes Simplex Type 2 Infection and Protects Mice Vaginal Microbiome

The G2-S16 polyanionic carbosilane dendrimer is a promising microbicide that inhibits HSV-2 infection in vitro and in vivo in mice models. This G2-S16 dendrimer inhibits HSV-2 infection even in the presence of semen. Murine models, such as BALB/c female mice, are generally used to characterize host-...

Descripción completa

Detalles Bibliográficos
Autores principales: Guerrero-Beltrán, Carlos, Garcia-Heredia, Inmaculada, Ceña-Diez, Rafael, Rodriguez-Izquierdo, Ignacio, Serramía, María Jesús, Martinez-Hernandez, Francisco, Lluesma-Gomez, Mónica, Martinez-Garcia, Manuel, Muñoz-Fernández, María Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356682/
https://www.ncbi.nlm.nih.gov/pubmed/32512836
http://dx.doi.org/10.3390/pharmaceutics12060515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356682/
https://www.ncbi.nlm.nih.gov/pubmed/32512836
http://dx.doi.org/10.3390/pharmaceutics12060515

Ejemplares similares