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Cationic Dendrimer G2-S16 Inhibits Herpes Simplex Type 2 Infection and Protects Mice Vaginal Microbiome

The G2-S16 polyanionic carbosilane dendrimer is a promising microbicide that inhibits HSV-2 infection in vitro and in vivo in mice models. This G2-S16 dendrimer inhibits HSV-2 infection even in the presence of semen. Murine models, such as BALB/c female mice, are generally used to characterize host-...

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Detalles Bibliográficos
Autores principales:	Guerrero-Beltrán, Carlos, Garcia-Heredia, Inmaculada, Ceña-Diez, Rafael, Rodriguez-Izquierdo, Ignacio, Serramía, María Jesús, Martinez-Hernandez, Francisco, Lluesma-Gomez, Mónica, Martinez-Garcia, Manuel, Muñoz-Fernández, María Ángeles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356682/ https://www.ncbi.nlm.nih.gov/pubmed/32512836 http://dx.doi.org/10.3390/pharmaceutics12060515

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