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Methicillin-Resistant Staphylococcus aureus (MRSA) in Poultry Species in Algeria: Long-Term Study on Prevalence and Antimicrobial Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) is a well-known pathogen with a serious impact on human and veterinary public health. To determine antibiotic resistance of MRSA in poultry, 4248 nasal swabs were collected from 840 poultry farms in 18 different Wilayas (provinces) of Algeria. Swabs...

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Autores principales: Benrabia, Ismahane, Hamdi, Taha M., Shehata, Awad A., Neubauer, Heinrich, Wareth, Gamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356745/
https://www.ncbi.nlm.nih.gov/pubmed/32349228
http://dx.doi.org/10.3390/vetsci7020054
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author Benrabia, Ismahane
Hamdi, Taha M.
Shehata, Awad A.
Neubauer, Heinrich
Wareth, Gamal
author_facet Benrabia, Ismahane
Hamdi, Taha M.
Shehata, Awad A.
Neubauer, Heinrich
Wareth, Gamal
author_sort Benrabia, Ismahane
collection PubMed
description Methicillin-resistant Staphylococcus aureus (MRSA) is a well-known pathogen with a serious impact on human and veterinary public health. To determine antibiotic resistance of MRSA in poultry, 4248 nasal swabs were collected from 840 poultry farms in 18 different Wilayas (provinces) of Algeria. Swabs were collected between 2011 and 2018 from breeding hens, laying hens, broilers, and turkeys. Identification was carried out by the classical culture methods, and the disc diffusion test was used to determine the antibiotic resistance patterns. S. aureus was isolated from 477 (56.8%) farms, and flock prevalence was 52.8%, 48.8%, 48.4%, and 75.6% in breeding hens, laying hens, broilers, and turkeys, respectively. MRSA was isolated from 252 (30%) farms and flock prevalence was 22%, 33.5%, 27.4%, and 36%, respectively. As expected, all MRSA isolates were resistant to cefoxitin, penicillin G, amoxicillin/clavulanic acid, and oxacillin. High levels of resistance were found for tetracycline (82.5%), erythromycin (70.6%), clindamycin (68.6%), and ciprofloxacin (50%). Almost all isolates were susceptible to vancomycin (100%) and mupirocin and rifampicin (99.2%), followed by chloramphenicol (82.3%), and gentamicin (76%). This moderate proportion of MRSA in poultry poses a considerable risk to public health. The results of this study highlight the need for control programs that encompass primary animal production and the food chain to mitigate contamination and spread of MRSA in the poultry industry of Algeria, and consequently to humans.
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spelling pubmed-73567452020-07-22 Methicillin-Resistant Staphylococcus aureus (MRSA) in Poultry Species in Algeria: Long-Term Study on Prevalence and Antimicrobial Resistance Benrabia, Ismahane Hamdi, Taha M. Shehata, Awad A. Neubauer, Heinrich Wareth, Gamal Vet Sci Article Methicillin-resistant Staphylococcus aureus (MRSA) is a well-known pathogen with a serious impact on human and veterinary public health. To determine antibiotic resistance of MRSA in poultry, 4248 nasal swabs were collected from 840 poultry farms in 18 different Wilayas (provinces) of Algeria. Swabs were collected between 2011 and 2018 from breeding hens, laying hens, broilers, and turkeys. Identification was carried out by the classical culture methods, and the disc diffusion test was used to determine the antibiotic resistance patterns. S. aureus was isolated from 477 (56.8%) farms, and flock prevalence was 52.8%, 48.8%, 48.4%, and 75.6% in breeding hens, laying hens, broilers, and turkeys, respectively. MRSA was isolated from 252 (30%) farms and flock prevalence was 22%, 33.5%, 27.4%, and 36%, respectively. As expected, all MRSA isolates were resistant to cefoxitin, penicillin G, amoxicillin/clavulanic acid, and oxacillin. High levels of resistance were found for tetracycline (82.5%), erythromycin (70.6%), clindamycin (68.6%), and ciprofloxacin (50%). Almost all isolates were susceptible to vancomycin (100%) and mupirocin and rifampicin (99.2%), followed by chloramphenicol (82.3%), and gentamicin (76%). This moderate proportion of MRSA in poultry poses a considerable risk to public health. The results of this study highlight the need for control programs that encompass primary animal production and the food chain to mitigate contamination and spread of MRSA in the poultry industry of Algeria, and consequently to humans. MDPI 2020-04-27 /pmc/articles/PMC7356745/ /pubmed/32349228 http://dx.doi.org/10.3390/vetsci7020054 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Benrabia, Ismahane
Hamdi, Taha M.
Shehata, Awad A.
Neubauer, Heinrich
Wareth, Gamal
Methicillin-Resistant Staphylococcus aureus (MRSA) in Poultry Species in Algeria: Long-Term Study on Prevalence and Antimicrobial Resistance
title Methicillin-Resistant Staphylococcus aureus (MRSA) in Poultry Species in Algeria: Long-Term Study on Prevalence and Antimicrobial Resistance
title_full Methicillin-Resistant Staphylococcus aureus (MRSA) in Poultry Species in Algeria: Long-Term Study on Prevalence and Antimicrobial Resistance
title_fullStr Methicillin-Resistant Staphylococcus aureus (MRSA) in Poultry Species in Algeria: Long-Term Study on Prevalence and Antimicrobial Resistance
title_full_unstemmed Methicillin-Resistant Staphylococcus aureus (MRSA) in Poultry Species in Algeria: Long-Term Study on Prevalence and Antimicrobial Resistance
title_short Methicillin-Resistant Staphylococcus aureus (MRSA) in Poultry Species in Algeria: Long-Term Study on Prevalence and Antimicrobial Resistance
title_sort methicillin-resistant staphylococcus aureus (mrsa) in poultry species in algeria: long-term study on prevalence and antimicrobial resistance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356745/
https://www.ncbi.nlm.nih.gov/pubmed/32349228
http://dx.doi.org/10.3390/vetsci7020054
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