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Disability of Dialysis Patients and the Condition of Blood Vessels

The number of elderly hemodialysis patients is constantly increasing worldwide. This population has a high burden of comorbid conditions, which impair daily activities. The aim of the study was to analyze problems of disability in hemodialysis patients in the context of cardiovascular (CV) complicat...

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Autores principales: Gołębiowski, Tomasz, Kusztal, Mariusz, Konieczny, Andrzej, Letachowicz, Krzysztof, Gawryś, Ada, Skolimowska, Beata, Ostrowska, Bożena, Zmonarski, Sławomir, Janczak, Dariusz, Krajewska, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356767/
https://www.ncbi.nlm.nih.gov/pubmed/32531965
http://dx.doi.org/10.3390/jcm9061806
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author Gołębiowski, Tomasz
Kusztal, Mariusz
Konieczny, Andrzej
Letachowicz, Krzysztof
Gawryś, Ada
Skolimowska, Beata
Ostrowska, Bożena
Zmonarski, Sławomir
Janczak, Dariusz
Krajewska, Magdalena
author_facet Gołębiowski, Tomasz
Kusztal, Mariusz
Konieczny, Andrzej
Letachowicz, Krzysztof
Gawryś, Ada
Skolimowska, Beata
Ostrowska, Bożena
Zmonarski, Sławomir
Janczak, Dariusz
Krajewska, Magdalena
author_sort Gołębiowski, Tomasz
collection PubMed
description The number of elderly hemodialysis patients is constantly increasing worldwide. This population has a high burden of comorbid conditions, which impair daily activities. The aim of the study was to analyze problems of disability in hemodialysis patients in the context of cardiovascular (CV) complications and vascular condition. In this cross-sectional study, 129 patients (mean age 64.5) were enrolled. The degree of disability in Barthel index (Bi) and 10-year cardiovascular risk (QRISK(®)3) were assessed. A Mobil-O-Graph monitor was used for measuring hemodynamic parameters. Only 6.2% of patients were professionally active, 19% used a wheelchair for transport, and 16% used crutches. More than half (51%) were independent in everyday activities reaching 80–100 points on Bi. The rest, with Bi < 80, were considered as dependent. The most common causes of disability were CV complications. The independent group (80–100 points) was characterized by significantly lower pulse wave velocity (PWV) and lower QRISK(®)3 compared to dependent patients. The degree of disability negatively correlated with age, PWV, and QRISK(®)3. Multivariate logistic regression revealed that disability (Bi < 80) was independently associated with CV events in the past adjusted odds ratio (adj.OR) 4.83 (95% confidence interval (95% CI): 1.74–13.41) and higher PWV adj.OR 1.45 (95% CI: 1.15–1.82). Our results indicate that CV diseases are the most important cause of functional impairment.
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spelling pubmed-73567672020-07-22 Disability of Dialysis Patients and the Condition of Blood Vessels Gołębiowski, Tomasz Kusztal, Mariusz Konieczny, Andrzej Letachowicz, Krzysztof Gawryś, Ada Skolimowska, Beata Ostrowska, Bożena Zmonarski, Sławomir Janczak, Dariusz Krajewska, Magdalena J Clin Med Article The number of elderly hemodialysis patients is constantly increasing worldwide. This population has a high burden of comorbid conditions, which impair daily activities. The aim of the study was to analyze problems of disability in hemodialysis patients in the context of cardiovascular (CV) complications and vascular condition. In this cross-sectional study, 129 patients (mean age 64.5) were enrolled. The degree of disability in Barthel index (Bi) and 10-year cardiovascular risk (QRISK(®)3) were assessed. A Mobil-O-Graph monitor was used for measuring hemodynamic parameters. Only 6.2% of patients were professionally active, 19% used a wheelchair for transport, and 16% used crutches. More than half (51%) were independent in everyday activities reaching 80–100 points on Bi. The rest, with Bi < 80, were considered as dependent. The most common causes of disability were CV complications. The independent group (80–100 points) was characterized by significantly lower pulse wave velocity (PWV) and lower QRISK(®)3 compared to dependent patients. The degree of disability negatively correlated with age, PWV, and QRISK(®)3. Multivariate logistic regression revealed that disability (Bi < 80) was independently associated with CV events in the past adjusted odds ratio (adj.OR) 4.83 (95% confidence interval (95% CI): 1.74–13.41) and higher PWV adj.OR 1.45 (95% CI: 1.15–1.82). Our results indicate that CV diseases are the most important cause of functional impairment. MDPI 2020-06-10 /pmc/articles/PMC7356767/ /pubmed/32531965 http://dx.doi.org/10.3390/jcm9061806 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gołębiowski, Tomasz
Kusztal, Mariusz
Konieczny, Andrzej
Letachowicz, Krzysztof
Gawryś, Ada
Skolimowska, Beata
Ostrowska, Bożena
Zmonarski, Sławomir
Janczak, Dariusz
Krajewska, Magdalena
Disability of Dialysis Patients and the Condition of Blood Vessels
title Disability of Dialysis Patients and the Condition of Blood Vessels
title_full Disability of Dialysis Patients and the Condition of Blood Vessels
title_fullStr Disability of Dialysis Patients and the Condition of Blood Vessels
title_full_unstemmed Disability of Dialysis Patients and the Condition of Blood Vessels
title_short Disability of Dialysis Patients and the Condition of Blood Vessels
title_sort disability of dialysis patients and the condition of blood vessels
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356767/
https://www.ncbi.nlm.nih.gov/pubmed/32531965
http://dx.doi.org/10.3390/jcm9061806
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