Cargando…
Natural Function and Structural Modification of Climacostol, a Ciliate Secondary Metabolite
The review highlights the main results of two decades of research on climacostol (5-[(2Z)-non-2-en-1-yl]benzene-1,3-diol), the resorcinolic lipid produced and used by the ciliated protozoan Climacostomum virens for chemical defense against a wide range of predators, and to assist its carnivorous fee...
Autores principales: | Buonanno, Federico, Catalani, Elisabetta, Cervia, Davide, Cimarelli, Cristina, Marcantoni, Enrico, Ortenzi, Claudio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356801/ https://www.ncbi.nlm.nih.gov/pubmed/32471240 http://dx.doi.org/10.3390/microorganisms8060809 |
Ejemplares similares
-
Bioactivity and Structural Properties of Novel Synthetic Analogues of the Protozoan Toxin Climacostol
por: Buonanno, Federico, et al.
Publicado: (2019) -
Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells
por: Zecchini, Silvia, et al.
Publicado: (2018) -
The Natural Compound Climacostol as a Prodrug Strategy Based on pH Activation for Efficient Delivery of Cytotoxic Small Agents
por: Catalani, Elisabetta, et al.
Publicado: (2019) -
Climacostol reduces tumour progression in a mouse model of melanoma via the p53-dependent intrinsic apoptotic programme
por: Perrotta, Cristiana, et al.
Publicado: (2016) -
Preliminary Data Related to the Effect of Climacostol Produced by the Freshwater Ciliate Climacostomum virens on Human Adenovirus
por: Verani, Marco, et al.
Publicado: (2020)