Cargando…
Subcutaneous Administration of Apolipoprotein J-Derived Mimetic Peptide d-[113–122]apoJ Improves LDL and HDL Function and Prevents Atherosclerosis in LDLR-KO Mice
Mimetic peptides are potential therapeutic agents for atherosclerosis. d-[113–122]apolipoprotein (apo) J (d-[113–122]apoJ) is a 10-residue peptide that is predicted to form a class G* amphipathic helix 6 from apoJ; it shows anti-inflammatory and anti-atherogenic properties. In the present study, we...
Autores principales: | Rivas-Urbina, Andrea, Rull, Anna, Aldana-Ramos, Joile, Santos, David, Puig, Nuria, Farre-Cabrerizo, Nuria, Benitez, Sonia, Perez, Antonio, de Gonzalo-Calvo, David, Escola-Gil, Joan Carles, Julve, Josep, Ordoñez-Llanos, Jordi, Sanchez-Quesada, Jose Luis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356811/ https://www.ncbi.nlm.nih.gov/pubmed/32485898 http://dx.doi.org/10.3390/biom10060829 |
Ejemplares similares
-
Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis
por: Fernández-de-Retana, Sofía, et al.
Publicado: (2017) -
Plasma Clusterin (ApoJ) Levels Are Associated with Adiposity and Systemic Inflammation
por: Won, Jong Chul, et al.
Publicado: (2014) -
Brain ApoA-I, ApoJ and ApoE Immunodetection in Cerebral Amyloid Angiopathy
por: Camacho, Jessica, et al.
Publicado: (2019) -
Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice
por: de Retana, Sofía Fernández, et al.
Publicado: (2019) -
ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer’s disease
por: Ko, Yi-An, et al.
Publicado: (2022)