Cargando…

Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy

Atherosclerotic cardiovascular disease (ASCVD) shares many risk factors with atrial fibrillation (AF). Obtaining computed tomography images of the pulmonary veins (CTPV) before AF ablation procedures is common and can incidentally detect coronary artery calcification (CAC). The purpose of this study...

Descripción completa

Detalles Bibliográficos
Autores principales: Dunleavy, Michael P., Guha, Avirup, Cardona, Andrea, Fortuna, Christopher, Daoud, Emile G., Raman, Subha V., Harfi, Thura T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356831/
https://www.ncbi.nlm.nih.gov/pubmed/32481592
http://dx.doi.org/10.3390/jcm9061631
_version_ 1783558572199641088
author Dunleavy, Michael P.
Guha, Avirup
Cardona, Andrea
Fortuna, Christopher
Daoud, Emile G.
Raman, Subha V.
Harfi, Thura T.
author_facet Dunleavy, Michael P.
Guha, Avirup
Cardona, Andrea
Fortuna, Christopher
Daoud, Emile G.
Raman, Subha V.
Harfi, Thura T.
author_sort Dunleavy, Michael P.
collection PubMed
description Atherosclerotic cardiovascular disease (ASCVD) shares many risk factors with atrial fibrillation (AF). Obtaining computed tomography images of the pulmonary veins (CTPV) before AF ablation procedures is common and can incidentally detect coronary artery calcification (CAC). The purpose of this study was to investigate the prevalence of CAC on pre-ablation CTPV, the frequency of CAC reporting on CTPV reports, and its impact on statin therapy among patients hospitalized for AF procedures. We retrospectively evaluated consecutive patients undergoing CTPV and AF procedures from October 2016 to December 2017 in a single-center tertiary hospital. The patients’ demographic and clinical characteristics were analyzed. The CAC presence on CTPV was visually assessed. The severity was classified qualitatively. The statin therapy status was evaluated using the patient’s admission and discharge medication lists. A total of 638 subjects were included in our study, with 34.5% female. The mean age was 63.3 ± 10.8 years. CAC was detected in 70.1% of all patients, and in 58.1% of patients without a history of ASCVD. When present, CAC was documented in 92.6% of the clinical CTPV reports. While coronary artery atherosclerosis was present in a majority of AF patients, and its presence was widely reported, it was not associated with increased statin therapy at discharge.
format Online
Article
Text
id pubmed-7356831
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-73568312020-07-22 Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy Dunleavy, Michael P. Guha, Avirup Cardona, Andrea Fortuna, Christopher Daoud, Emile G. Raman, Subha V. Harfi, Thura T. J Clin Med Article Atherosclerotic cardiovascular disease (ASCVD) shares many risk factors with atrial fibrillation (AF). Obtaining computed tomography images of the pulmonary veins (CTPV) before AF ablation procedures is common and can incidentally detect coronary artery calcification (CAC). The purpose of this study was to investigate the prevalence of CAC on pre-ablation CTPV, the frequency of CAC reporting on CTPV reports, and its impact on statin therapy among patients hospitalized for AF procedures. We retrospectively evaluated consecutive patients undergoing CTPV and AF procedures from October 2016 to December 2017 in a single-center tertiary hospital. The patients’ demographic and clinical characteristics were analyzed. The CAC presence on CTPV was visually assessed. The severity was classified qualitatively. The statin therapy status was evaluated using the patient’s admission and discharge medication lists. A total of 638 subjects were included in our study, with 34.5% female. The mean age was 63.3 ± 10.8 years. CAC was detected in 70.1% of all patients, and in 58.1% of patients without a history of ASCVD. When present, CAC was documented in 92.6% of the clinical CTPV reports. While coronary artery atherosclerosis was present in a majority of AF patients, and its presence was widely reported, it was not associated with increased statin therapy at discharge. MDPI 2020-05-28 /pmc/articles/PMC7356831/ /pubmed/32481592 http://dx.doi.org/10.3390/jcm9061631 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dunleavy, Michael P.
Guha, Avirup
Cardona, Andrea
Fortuna, Christopher
Daoud, Emile G.
Raman, Subha V.
Harfi, Thura T.
Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy
title Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy
title_full Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy
title_fullStr Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy
title_full_unstemmed Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy
title_short Prevalence of Coronary Artery Calcification on Pre-Atrial Fibrillation Ablation CT Pulmonary Venograms and its Impact on Selection for Statin Therapy
title_sort prevalence of coronary artery calcification on pre-atrial fibrillation ablation ct pulmonary venograms and its impact on selection for statin therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356831/
https://www.ncbi.nlm.nih.gov/pubmed/32481592
http://dx.doi.org/10.3390/jcm9061631
work_keys_str_mv AT dunleavymichaelp prevalenceofcoronaryarterycalcificationonpreatrialfibrillationablationctpulmonaryvenogramsanditsimpactonselectionforstatintherapy
AT guhaavirup prevalenceofcoronaryarterycalcificationonpreatrialfibrillationablationctpulmonaryvenogramsanditsimpactonselectionforstatintherapy
AT cardonaandrea prevalenceofcoronaryarterycalcificationonpreatrialfibrillationablationctpulmonaryvenogramsanditsimpactonselectionforstatintherapy
AT fortunachristopher prevalenceofcoronaryarterycalcificationonpreatrialfibrillationablationctpulmonaryvenogramsanditsimpactonselectionforstatintherapy
AT daoudemileg prevalenceofcoronaryarterycalcificationonpreatrialfibrillationablationctpulmonaryvenogramsanditsimpactonselectionforstatintherapy
AT ramansubhav prevalenceofcoronaryarterycalcificationonpreatrialfibrillationablationctpulmonaryvenogramsanditsimpactonselectionforstatintherapy
AT harfithurat prevalenceofcoronaryarterycalcificationonpreatrialfibrillationablationctpulmonaryvenogramsanditsimpactonselectionforstatintherapy