Cargando…

Review of Pharmacological Strategies with Repurposed Drugs for Hereditary Hemorrhagic Telangiectasia Related Bleeding

The diagnosis of hereditary hemorrhagic telangiectasia (HHT) is based on the Curaçao criteria: epistaxis, telangiectases, arteriovenous malformations in internal organs, and family history. Genetically speaking, more than 90% of HHT patients show mutations in ENG or ACVRL1/ALK1 genes, both belonging...

Descripción completa

Detalles Bibliográficos
Autores principales:	Albiñana, Virginia, Cuesta, Angel M., de Rojas-P, Isabel, Gallardo-Vara, Eunate, Recio-Poveda, Lucía, Bernabéu, Carmelo, Botella, Luisa María
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356836/ https://www.ncbi.nlm.nih.gov/pubmed/32517280 http://dx.doi.org/10.3390/jcm9061766

Ejemplares similares

Research on potential biomarkers in hereditary hemorrhagic telangiectasia
por: Botella, Luisa-María, et al.
Publicado: (2015)

The Role of Propranolol as a Repurposed Drug in Rare Vascular Diseases
por: Cuesta, Angel M., et al.
Publicado: (2022)

Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia
por: Gallardo-Vara, Eunate, et al.
Publicado: (2018)

Differential Expression of Circulating Plasma miRNA-370 and miRNA-10a from Patients with Hereditary Hemorrhagic Telangiectasia
por: Ruiz-Llorente, Lidia, et al.
Publicado: (2020)

Copy number variations in endoglin locus: mapping of large deletions in Spanish families with hereditary hemorrhagic telangiectasia type 1
por: Fontalba, Ana, et al.
Publicado: (2013)

Mutation affecting the proximal promoter of Endoglin as the origin of hereditary hemorrhagic telangiectasia type 1
por: Albiñana, Virginia, et al.
Publicado: (2017)

Mutation study of Spanish patients with Hereditary Hemorrhagic Telangiectasia
por: Fontalba, Ana, et al.
Publicado: (2008)

Propranolol: A “Pick and Roll” Team Player in Benign Tumors and Cancer Therapies
por: Albiñana, Virginia, et al.
Publicado: (2022)

SARS-CoV-2 Infection in Hereditary Hemorrhagic Telangiectasia Patients Suggests Less Clinical Impact Than in the General Population
por: Marcos, Sol, et al.
Publicado: (2021)

5'UTR mutations of ENG cause hereditary hemorrhagic telangiectasia
por: Damjanovich, Kristy, et al.
Publicado: (2011)

Potential Second-Hits in Hereditary Hemorrhagic Telangiectasia
por: Bernabeu, Carmelo, et al.
Publicado: (2020)

Functional Alterations Involved in Increased Bleeding in Hereditary Hemorrhagic Telangiectasia Mouse Models
por: Egido-Turrión, Cristina, et al.
Publicado: (2022)

Bevacizumab and gastrointestinal bleeding in hereditary hemorrhagic telangiectasia
por: Ou, George, et al.
Publicado: (2016)

Hereditary Hemorrhagic Telangiectasia: Diagnosis and Management
por: Angel, Cuesta M.
Publicado: (2022)

Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia
por: Faughnan, Marie E., et al.
Publicado: (2018)

Targeting β2-Adrenergic Receptors Shows Therapeutical Benefits in Clear Cell Renal Cell Carcinoma from Von Hippel–Lindau Disease
por: Albiñana, Virginia, et al.
Publicado: (2020)

Significant Hematochezia and Intracranial Bleeding in Neonatal Hereditary Hemorrhagic Telangiectasia
por: Merves, Matthew, et al.
Publicado: (2019)

Tamoxifen Therapy for Recurrent Mucosal Bleeding in Hereditary Hemorrhagic Telangiectasia
por: Yung, Stephanie, et al.
Publicado: (2021)

Management of Refractory Gastrointestinal Bleeding in Hereditary Hemorrhagic Telangiectasia with Bevacizumab
por: Masood, Muaaz, et al.
Publicado: (2021)

Safety of thalidomide and bevacizumab in patients with hereditary hemorrhagic telangiectasia
por: Buscarini, Elisabetta, et al.
Publicado: (2019)

Hereditary Hemorrhagic Telangiectasia
por: Kamath, Nagesh, et al.
Publicado: (2015)

Pazopanib for severe bleeding and transfusion-dependent anemia in hereditary hemorrhagic telangiectasia
por: Parambil, Joseph G., et al.
Publicado: (2021)

Tacrolimus in Gastrointestinal Bleeding in a Young Boy With Hereditary Hemorrhagic Telangiectasia
por: Pruijsen, Jessica M., et al.
Publicado: (2021)

Aflibercept for Gastrointestinal Bleeding in Hereditary Hemorrhagic Telangiectasia: A Case Report
por: Villanueva, Bernat, et al.
Publicado: (2023)

Imaging of Hereditary Hemorrhagic Telangiectasia
por: Carette, Marie-France, et al.
Publicado: (2008)

CLN5 in heterozygosis may protect against the development of tumors in a VHL patient
por: de Rojas-P, Isabel, et al.
Publicado: (2020)

Gastrointestinal Bleeding in Patients with Hereditary Hemorrhagic Telangiectasia: Risk Factors and Endoscopic Findings
por: Mora-Luján, José María, et al.
Publicado: (2019)

Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury
por: Gallardo-Vara, Eunate, et al.
Publicado: (2016)

Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease
por: Albiñana, Virginia, et al.
Publicado: (2017)

An international, multicenter study of intravenous bevacizumab for bleeding in hereditary hemorrhagic telangiectasia: the InHIBIT-Bleed study
por: Al-Samkari, Hanny, et al.
Publicado: (2020)

Characterization of a family mutation in the 5’ untranslated region of the endoglin gene causative of hereditary hemorrhagic telangiectasia
por: Ruiz-Llorente, Lidia, et al.
Publicado: (2019)

Optimal management of hereditary hemorrhagic telangiectasia
por: Garg, Neetika, et al.
Publicado: (2014)

Hereditary Hemorrhagic Telangiectasia with Unusual Associations
por: Jain, Dheeraj, et al.
Publicado: (2015)

Severity score for hereditary hemorrhagic telangiectasia
por: Latino, Giuseppe A, et al.
Publicado: (2014)

Pericytes as targets in hereditary hemorrhagic telangiectasia
por: Thalgott, Jérémy, et al.
Publicado: (2015)

Hypercoagulability in hereditary hemorrhagic telangiectasia with epilepsy
por: Finsterer, Josef, et al.
Publicado: (2015)

Splenic Involvement in Hereditary Hemorrhagic Telangiectasia
por: Takamatsu, Susumu, et al.
Publicado: (2016)

Hereditary hemorrhagic telangiectasia with hemothorax in pregnancy
por: Raiya, Sagar, et al.
Publicado: (2017)

Hereditary Hemorrhagic Telangiectasia and Refractory Ascites
por: Thandassery, Ragesh B., et al.
Publicado: (2020)

Future treatments for hereditary hemorrhagic telangiectasia
por: Robert, Florian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qq92neijok5nhj28vsjnug3al5