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Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus
The increasing prevalence of drug-resistant influenza viruses emphasizes the need for new antiviral countermeasures. The M2 protein of influenza A is a proton-gated, proton-selective ion channel, which is essential for influenza replication and an established antiviral target. However, all currently...
Autores principales: | Duncan, Maggie C., Onguéné, Pascal Amoa, Kihara, Ibuki, Nebangwa, Derrick N., Naidu, Maya E., Williams, David E., Balgi, Aruna D., Andrae-Marobela, Kerstin, Roberge, Michel, Andersen, Raymond J., Niikura, Masahiro, Ntie-Kang, Fidele, Tietjen, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356874/ https://www.ncbi.nlm.nih.gov/pubmed/32599753 http://dx.doi.org/10.3390/molecules25122903 |
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