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Overexpression of lpxT Gene in Escherichia coli Inhibits Cell Division and Causes Envelope Defects without Changing the Overall Phosphorylation Level of Lipid A

LpxT is an inner membrane protein that transfers a phosphate group from the essential lipid undecaprenyl pyrophosphate (C-55PP) to the lipid A moiety of lipopolysaccharide, generating a lipid A tris-phosphorylated species. The protein is encoded by the non-essential lpxT gene, which is conserved in...

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Detalles Bibliográficos
Autores principales: Falchi, Federica A., Di Lorenzo, Flaviana, Pizzoccheri, Roberto, Casino, Gianluca, Paroni, Moira, Forti, Francesca, Molinaro, Antonio, Briani, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356881/
https://www.ncbi.nlm.nih.gov/pubmed/32486329
http://dx.doi.org/10.3390/microorganisms8060826