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Overexpression of lpxT Gene in Escherichia coli Inhibits Cell Division and Causes Envelope Defects without Changing the Overall Phosphorylation Level of Lipid A
LpxT is an inner membrane protein that transfers a phosphate group from the essential lipid undecaprenyl pyrophosphate (C-55PP) to the lipid A moiety of lipopolysaccharide, generating a lipid A tris-phosphorylated species. The protein is encoded by the non-essential lpxT gene, which is conserved in...
Autores principales: | Falchi, Federica A., Di Lorenzo, Flaviana, Pizzoccheri, Roberto, Casino, Gianluca, Paroni, Moira, Forti, Francesca, Molinaro, Antonio, Briani, Federica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356881/ https://www.ncbi.nlm.nih.gov/pubmed/32486329 http://dx.doi.org/10.3390/microorganisms8060826 |
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