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Autocrine TGF-β1 Maintains the Stability of Foxp3(+) Regulatory T Cells via IL-12Rβ2 Downregulation

Transforming growth factor beta 1 (TGF-β1) is an immunosuppresive cytokine that plays an essential role in immune homeostasis. It is well known that regulatory T (Treg) cells express TGF-β1; however, the role of autocrine TGF-β1 in the development, function, and stability of Treg cells remains poorl...

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Detalles Bibliográficos
Autores principales:	Choi, Garam, Na, Hyeongjin, Kuen, Da-Sol, Kim, Byung-Seok, Chung, Yeonseok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356964/ https://www.ncbi.nlm.nih.gov/pubmed/32471185 http://dx.doi.org/10.3390/biom10060819

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