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A Population Pharmacokinetic and Pharmacodynamic Model of CKD-519

CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor that is being developed for dyslipidemia. Even though CKD-519 has shown potent CETP inhibition, the exposure of CKD-519 was highly varied, depending on food and dose. For highly variable exposure drugs, it is cruci...

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Detalles Bibliográficos
Autores principales:	Kim, Choon Ok, Jeon, Sangil, Han, Seunghoon, Park, Min Soo, Yim, Dong-Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356970/ https://www.ncbi.nlm.nih.gov/pubmed/32575566 http://dx.doi.org/10.3390/pharmaceutics12060573

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