Cargando…

Characterizing the Role of SMYD2 in Mammalian Embryogenesis—Future Directions

The SET and MYND domain-containing (SMYD) family of lysine methyltransferases are essential in several mammalian developmental pathways. Although predominantly expressed in the heart, the role of SMYD2 in heart development has yet to be fully elucidated and has even been shown to be dispensable in a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jarrell, Dillon K., Hassell, Kelly N., Crans, Debbie C., Lanning, Shari, Brown, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357037/ https://www.ncbi.nlm.nih.gov/pubmed/32408548 http://dx.doi.org/10.3390/vetsci7020063

Ejemplares similares

Structural Analysis of SMYD3 Lysine Methyltransferase for the Development of Competitive and Specific Enzyme Inhibitors
por: Jarrell, Dillon K., et al.
Publicado: (2021)

In Silico/In Vitro Hit-to-Lead Methodology Yields SMYD3 Inhibitor That Eliminates Unrestrained Proliferation of Breast Carcinoma Cells
por: Alshiraihi, Ilham M., et al.
Publicado: (2020)

Targeting Epigenetic Changes Mediated by Members of the SMYD Family of Lysine Methyltransferases
por: Padilla, Alyssa, et al.
Publicado: (2023)

The Lysine Methyltransferase SMYD2 Is Required for Definite Hematopoietic Stem Cell Production in the Mouse Embryo
por: Edwards, Melissa A., et al.
Publicado: (2020)

Clinical Sciences—Leading the Way in Competency-Based Biomedical Education
por: Brown, Mark A., et al.
Publicado: (2020)

Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis
por: Fujii, Tomoaki, et al.
Publicado: (2016)

Molecular recording of mammalian embryogenesis
por: Chan, Michelle M., et al.
Publicado: (2019)

Biophysical models of early mammalian embryogenesis
por: Cockerell, Alaina, et al.
Publicado: (2023)

Engineering Myocardium for Heart Regeneration—Advancements, Considerations, and Future Directions
por: Jarrell, Dillon K., et al.
Publicado: (2020)

Rebooting the Epigenomes during Mammalian Early Embryogenesis
por: Xia, Weikun, et al.
Publicado: (2020)

A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis
por: Mak, Winifred, et al.
Publicado: (2018)

DNA Polymerase δ Is Required for Early Mammalian Embryogenesis
por: Uchimura, Arikuni, et al.
Publicado: (2009)

The roles of SMYD4 in epigenetic regulation of cardiac development in zebrafish
por: Xiao, Deyong, et al.
Publicado: (2018)

Upregulation of SMYD3 and SMYD3 VNTR 3/3 polymorphism increase the risk of hepatocellular carcinoma
por: Binh, Mai Thanh, et al.
Publicado: (2020)

Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3
por: Foreman, Kenneth W., et al.
Publicado: (2011)

The role of the innate immune response regulatory gene ABCF1 in mammalian embryogenesis and development
por: Wilcox, Sara M., et al.
Publicado: (2017)

Cardiac Deletion of Smyd2 Is Dispensable for Mouse Heart Development
por: Diehl, Florian, et al.
Publicado: (2010)

Open questions on the biological roles of first-row transition metals
por: Crans, Debbie C., et al.
Publicado: (2020)

The Tempo of Mammalian Embryogenesis: Variation in the Pace of Brain and Body Development
por: Halley, Andrew C.
Publicado: (2022)

Anticancer Impact of Nitric Oxide (NO) and NO Combination with SMYD-3 Inhibitor on Breast Carcinomas
por: Gordon, Jenna L., et al.
Publicado: (2021)

SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin
por: Li, Dali, et al.
Publicado: (2009)

Expression and Functional Characterization of Smyd1a in Myofibril Organization of Skeletal Muscles
por: Gao, Jie, et al.
Publicado: (2014)

Synthesis and Characterization of Partially and Fully Saturated Menaquinone Derivatives
por: Koehn, Jordan T., et al.
Publicado: (2018)

SMYD2 glutathionylation contributes to degradation of sarcomeric proteins
por: Munkanatta Godage, Dhanushka N. P., et al.
Publicado: (2018)

Lysine Methyltransferase SMYD1 Regulates Myogenesis via skNAC Methylation
por: Zhu, Li, et al.
Publicado: (2023)

eMouseAtlas: An atlas-based resource for understanding mammalian embryogenesis
por: Armit, Chris, et al.
Publicado: (2017)

Network analyses elucidate the role of SMYD3 in esophageal squamous cell carcinoma
por: Liu, Xinning, et al.
Publicado: (2017)

The lysine methyltransferase SMYD2 is required for normal lymphocyte development and survival of hematopoietic leukemias.
por: Brown, Mark A., et al.
Publicado: (2020)

Evolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal Species
por: Calpena, Eduardo, et al.
Publicado: (2015)

SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells
por: Toghill, Bradley J., et al.
Publicado: (2018)

Functional genomics of HMGN3a and SMARCAL1 in early mammalian embryogenesis
por: Uzun, Alper, et al.
Publicado: (2009)

Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis
por: Boroviak, Thorsten, et al.
Publicado: (2015)

mtDNA Chromatin-like Organization Is Gradually Established during Mammalian Embryogenesis
por: Marom, Shani, et al.
Publicado: (2019)

EmAtlas: a comprehensive atlas for exploring spatiotemporal activation in mammalian embryogenesis
por: Zheng, Lei, et al.
Publicado: (2022)

SMYD1, an SRF-Interacting Partner, Is Involved in Angiogenesis
por: Ye, Xiangli, et al.
Publicado: (2016)

SMYD proteins in immunity: dawning of a new era
por: Doughan, Maysaa, et al.
Publicado: (2016)

Histone methyltransferase SMYD2: ubiquitous regulator of disease
por: Yi, Xin, et al.
Publicado: (2019)

Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation
por: Thomenius, Michael J., et al.
Publicado: (2018)

Integrated Microfluidic Device for Drug Studies of Early C. Elegans Embryogenesis
por: Dong, Li, et al.
Publicado: (2018)

Indispensable Roles of Plastids in Arabidopsis thaliana Embryogenesis
por: Hsu, Shih-Chi, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_2ckl6gg8l1u0amhp0jrdl00v3t