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Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review
Clostridium difficile infection is a common nosocomial infection in US hospitals, accounting for approximately 12 800 deaths annually in the United States. These infections are often associated with the use of antibiotics, which can alter the gut microbiome and thus render patients susceptible to C...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357048/ https://www.ncbi.nlm.nih.gov/pubmed/32646242 http://dx.doi.org/10.1177/2324709620941315 |
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author | Parvataneni, Swetha Dasari, Avinash R. |
author_facet | Parvataneni, Swetha Dasari, Avinash R. |
author_sort | Parvataneni, Swetha |
collection | PubMed |
description | Clostridium difficile infection is a common nosocomial infection in US hospitals, accounting for approximately 12 800 deaths annually in the United States. These infections are often associated with the use of antibiotics, which can alter the gut microbiome and thus render patients susceptible to C difficile infection. C difficile is often spread via fecal oral transmission. Multiple medications have been developed, but recurrence rates reach 60% after treatment. Recent data have shown that zinc supplementation decreases the recurrence of C difficile infection. In this article, we present a case of recurrent C difficile infection with zinc deficiency in which zinc supplementation improved the symptoms and reduced the incidence of recurrence. |
format | Online Article Text |
id | pubmed-7357048 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-73570482020-07-21 Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review Parvataneni, Swetha Dasari, Avinash R. J Investig Med High Impact Case Rep Case Report Clostridium difficile infection is a common nosocomial infection in US hospitals, accounting for approximately 12 800 deaths annually in the United States. These infections are often associated with the use of antibiotics, which can alter the gut microbiome and thus render patients susceptible to C difficile infection. C difficile is often spread via fecal oral transmission. Multiple medications have been developed, but recurrence rates reach 60% after treatment. Recent data have shown that zinc supplementation decreases the recurrence of C difficile infection. In this article, we present a case of recurrent C difficile infection with zinc deficiency in which zinc supplementation improved the symptoms and reduced the incidence of recurrence. SAGE Publications 2020-07-10 /pmc/articles/PMC7357048/ /pubmed/32646242 http://dx.doi.org/10.1177/2324709620941315 Text en © 2020 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Parvataneni, Swetha Dasari, Avinash R. Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review |
title | Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review |
title_full | Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review |
title_fullStr | Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review |
title_full_unstemmed | Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review |
title_short | Zinc Level and Its Role in Recurrent Clostridium difficile Infection: A Case Report and Literature Review |
title_sort | zinc level and its role in recurrent clostridium difficile infection: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357048/ https://www.ncbi.nlm.nih.gov/pubmed/32646242 http://dx.doi.org/10.1177/2324709620941315 |
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