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Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1α Activation
Aging is accompanied by the accumulation of senescent cells that alter intercellular communication, thereby impairing tissue homeostasis and reducing organ regenerative potential. Recently, the administration of mesenchymal stem cells (MSC)-derived extracellular vesicles has proven to be more effect...
Autores principales: | Mas-Bargues, Cristina, Sanz-Ros, Jorge, Román-Domínguez, Aurora, Gimeno-Mallench, Lucia, Inglés, Marta, Viña, José, Borrás, Consuelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357081/ https://www.ncbi.nlm.nih.gov/pubmed/32630449 http://dx.doi.org/10.3390/biom10060957 |
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