Cargando…
Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum
It is commonly assumed that asexual lineages are short-lived evolutionarily, yet many asexual organisms can generate genetic and phenotypic variation, providing an avenue for further evolution. Previous work on the asexual plant pathogen Phytophthora ramorum NA1 revealed considerable genetic variati...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357085/ https://www.ncbi.nlm.nih.gov/pubmed/32580470 http://dx.doi.org/10.3390/microorganisms8060940 |
_version_ | 1783558631996784640 |
---|---|
author | Yuzon, Jennifer David Travadon, Renaud Malar C, Mathu Tripathy, Sucheta Rank, Nathan Mehl, Heather K. Rizzo, David M. Cobb, Richard Small, Corinn Tang, Tiffany McCown, Haley E. Garbelotto, Matteo Kasuga, Takao |
author_facet | Yuzon, Jennifer David Travadon, Renaud Malar C, Mathu Tripathy, Sucheta Rank, Nathan Mehl, Heather K. Rizzo, David M. Cobb, Richard Small, Corinn Tang, Tiffany McCown, Haley E. Garbelotto, Matteo Kasuga, Takao |
author_sort | Yuzon, Jennifer David |
collection | PubMed |
description | It is commonly assumed that asexual lineages are short-lived evolutionarily, yet many asexual organisms can generate genetic and phenotypic variation, providing an avenue for further evolution. Previous work on the asexual plant pathogen Phytophthora ramorum NA1 revealed considerable genetic variation in the form of Structural Variants (SVs). To better understand how SVs arise and their significance to the California NA1 population, we studied the evolutionary histories of SVs and the forest conditions associated with their emergence. Ancestral state reconstruction suggests that SVs arose by somatic mutations among multiple independent lineages, rather than by recombination. We asked if this unusual phenomenon of parallel evolution between isolated populations is transmitted to extant lineages and found that SVs persist longer in a population if their genetic background had a lower mutation load. Genetic parallelism was also found in geographically distant demes where forest conditions such as host density, solar radiation, and temperature, were similar. Parallel SVs overlap with genes involved in pathogenicity such as RXLRs and have the potential to change the course of an epidemic. By combining genomics and environmental data, we identified an unexpected pattern of repeated evolution in an asexual population and identified environmental factors potentially driving this phenomenon. |
format | Online Article Text |
id | pubmed-7357085 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73570852020-07-23 Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum Yuzon, Jennifer David Travadon, Renaud Malar C, Mathu Tripathy, Sucheta Rank, Nathan Mehl, Heather K. Rizzo, David M. Cobb, Richard Small, Corinn Tang, Tiffany McCown, Haley E. Garbelotto, Matteo Kasuga, Takao Microorganisms Article It is commonly assumed that asexual lineages are short-lived evolutionarily, yet many asexual organisms can generate genetic and phenotypic variation, providing an avenue for further evolution. Previous work on the asexual plant pathogen Phytophthora ramorum NA1 revealed considerable genetic variation in the form of Structural Variants (SVs). To better understand how SVs arise and their significance to the California NA1 population, we studied the evolutionary histories of SVs and the forest conditions associated with their emergence. Ancestral state reconstruction suggests that SVs arose by somatic mutations among multiple independent lineages, rather than by recombination. We asked if this unusual phenomenon of parallel evolution between isolated populations is transmitted to extant lineages and found that SVs persist longer in a population if their genetic background had a lower mutation load. Genetic parallelism was also found in geographically distant demes where forest conditions such as host density, solar radiation, and temperature, were similar. Parallel SVs overlap with genes involved in pathogenicity such as RXLRs and have the potential to change the course of an epidemic. By combining genomics and environmental data, we identified an unexpected pattern of repeated evolution in an asexual population and identified environmental factors potentially driving this phenomenon. MDPI 2020-06-22 /pmc/articles/PMC7357085/ /pubmed/32580470 http://dx.doi.org/10.3390/microorganisms8060940 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yuzon, Jennifer David Travadon, Renaud Malar C, Mathu Tripathy, Sucheta Rank, Nathan Mehl, Heather K. Rizzo, David M. Cobb, Richard Small, Corinn Tang, Tiffany McCown, Haley E. Garbelotto, Matteo Kasuga, Takao Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum |
title | Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum |
title_full | Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum |
title_fullStr | Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum |
title_full_unstemmed | Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum |
title_short | Asexual Evolution and Forest Conditions Drive Genetic Parallelism in Phytophthora ramorum |
title_sort | asexual evolution and forest conditions drive genetic parallelism in phytophthora ramorum |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357085/ https://www.ncbi.nlm.nih.gov/pubmed/32580470 http://dx.doi.org/10.3390/microorganisms8060940 |
work_keys_str_mv | AT yuzonjenniferdavid asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT travadonrenaud asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT malarcmathu asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT tripathysucheta asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT ranknathan asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT mehlheatherk asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT rizzodavidm asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT cobbrichard asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT smallcorinn asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT tangtiffany asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT mccownhaleye asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT garbelottomatteo asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum AT kasugatakao asexualevolutionandforestconditionsdrivegeneticparallelisminphytophthoraramorum |