A Ribosome Interaction Surface Sensitive to mRNA GCN Periodicity

A longstanding challenge is to understand how ribosomes parse mRNA open reading frames (ORFs). Significantly, GCN codons are over-represented in the initial codons of ORFs of prokaryote and eukaryote mRNAs. We describe a ribosome rRNA-protein surface that interacts with an mRNA GCN codon when next i...

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Detalles Bibliográficos
Autores principales: Scopino, Kristen, Williams, Elliot, Elsayed, Abdelrahman, Barr, William A., Krizanc, Daniel, Thayer, Kelly M., Weir, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357141/
https://www.ncbi.nlm.nih.gov/pubmed/32503152
http://dx.doi.org/10.3390/biom10060849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357141/
https://www.ncbi.nlm.nih.gov/pubmed/32503152
http://dx.doi.org/10.3390/biom10060849

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