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A Ribosome Interaction Surface Sensitive to mRNA GCN Periodicity
A longstanding challenge is to understand how ribosomes parse mRNA open reading frames (ORFs). Significantly, GCN codons are over-represented in the initial codons of ORFs of prokaryote and eukaryote mRNAs. We describe a ribosome rRNA-protein surface that interacts with an mRNA GCN codon when next i...
Autores principales: | Scopino, Kristen, Williams, Elliot, Elsayed, Abdelrahman, Barr, William A., Krizanc, Daniel, Thayer, Kelly M., Weir, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357141/ https://www.ncbi.nlm.nih.gov/pubmed/32503152 http://dx.doi.org/10.3390/biom10060849 |
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