NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma

Tumor cells are characterized by unlimited proliferation and perturbed differentiation. Using single-cell RNA sequencing, we demonstrate that tumor cells in medulloblastoma (MB) retain their capacity to differentiate in a similar way as their normal originating cells, cerebellar granule neuron precu...

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Detalles Bibliográficos
Autores principales: Cheng, Yan, Liao, Shengyou, Xu, Gang, Hu, Jian, Guo, Duancheng, Du, Fang, Contreras, Alejandra, Cai, Kathy Q., Peri, Suraj, Wang, Yuan, Corney, David C., Noronha, Anne Marie, Chau, Lianne Q., Zhou, Ginger, Wiest, David L., Bellacosa, Alfonso, Wechsler-Reya, Robert J., Zhao, Yi, Yang, Zeng-jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357167/
https://www.ncbi.nlm.nih.gov/pubmed/32579914
http://dx.doi.org/10.1016/j.celrep.2020.107782

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