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Reprogramming and differentiation-dependent transcriptional alteration of DNA damage response and apoptosis genes in human induced pluripotent stem cells

Pluripotent stem cells (PSCs), such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), have a dual capability to self-renew and differentiate into all cell types necessary to develop an entire organism. Differentiation is associated with dynamic epigenetic alteration and tran...

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Detalles Bibliográficos
Autores principales: Shimada, Mikio, Tsukada, Kaima, Kagawa, Nozomi, Matsumoto, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357234/
https://www.ncbi.nlm.nih.gov/pubmed/31665364
http://dx.doi.org/10.1093/jrr/rrz057