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Reprogramming and differentiation-dependent transcriptional alteration of DNA damage response and apoptosis genes in human induced pluripotent stem cells
Pluripotent stem cells (PSCs), such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), have a dual capability to self-renew and differentiate into all cell types necessary to develop an entire organism. Differentiation is associated with dynamic epigenetic alteration and tran...
Autores principales: | Shimada, Mikio, Tsukada, Kaima, Kagawa, Nozomi, Matsumoto, Yoshihisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357234/ https://www.ncbi.nlm.nih.gov/pubmed/31665364 http://dx.doi.org/10.1093/jrr/rrz057 |
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