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Pharmacokinetics of high-dose tigecycline in critically ill patients with severe infections

BACKGROUND: In critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We designed a prospective observational study to describe the pharmacokinetic/pharmacodynamic (PK/PD) pro...

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Detalles Bibliográficos
Autores principales:	De Pascale, Gennaro, Lisi, Lucia, Ciotti, Gabriella Maria Pia, Vallecoccia, Maria Sole, Cutuli, Salvatore Lucio, Cascarano, Laura, Gelormini, Camilla, Bello, Giuseppe, Montini, Luca, Carelli, Simone, Di Gravio, Valentina, Tumbarello, Mario, Sanguinetti, Maurizio, Navarra, Pierluigi, Antonelli, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357259/ https://www.ncbi.nlm.nih.gov/pubmed/32661791 http://dx.doi.org/10.1186/s13613-020-00715-2

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