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Evaluation of different total Leishmania amazonensis antigens for the development of a first-generation vaccine formulated with a Toll-like receptor-3 agonist to prevent cutaneous leishmaniasis
BACKGROUND: Unfortunately, no any vaccine against leishmaniasis has been developed for human use. Therefore, a vaccine based on total Leishmania antigens could be a good and economic approach; and there are different methodologies to obtain these antigens. However, it is unknown whether the method t...
Autores principales: | Germanó, María José, Lozano, Esteban Sebastián, Sanchez, María Victoria, Bruna, Flavia Alejandra, García-Bustos, María Fernanda, Sosa Lochedino, Arianna Lourdes, Salomón, María Cristina, Fernandes, Ana Paula, Mackern-Oberti, Juan Pablo, Cargnelutti, Diego Esteban |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357544/ https://www.ncbi.nlm.nih.gov/pubmed/32667458 http://dx.doi.org/10.1590/0074-02760200067 |
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