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RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT

BACKGROUND: Tools such as MELD score and DRI are currently used to predict risks and benefits on liver allocation for transplantation. AIM: To evaluate the relation between donor quality and recipient severity on liver allocation. METHODS: Liver transplants performed in 2017 and 2018 were evaluated....

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Autores principales: de FREITAS, Alexandre Coutinho Teixeira, COELHO, Júlio Cezar Uili, WATANABE, Manoelle Risnei, LIMA, Rachel Lins das Chagas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357553/
https://www.ncbi.nlm.nih.gov/pubmed/32667529
http://dx.doi.org/10.1590/0102-672020190001e1499
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author de FREITAS, Alexandre Coutinho Teixeira
COELHO, Júlio Cezar Uili
WATANABE, Manoelle Risnei
LIMA, Rachel Lins das Chagas
author_facet de FREITAS, Alexandre Coutinho Teixeira
COELHO, Júlio Cezar Uili
WATANABE, Manoelle Risnei
LIMA, Rachel Lins das Chagas
author_sort de FREITAS, Alexandre Coutinho Teixeira
collection PubMed
description BACKGROUND: Tools such as MELD score and DRI are currently used to predict risks and benefits on liver allocation for transplantation. AIM: To evaluate the relation between donor quality and recipient severity on liver allocation. METHODS: Liver transplants performed in 2017 and 2018 were evaluated. Data were collected from Paraná’s State Government Registry. DRI was evaluated in relation to recipient MELD score and position on waiting list. RESULTS: It was observed relation between DRI and position on waiting list: higher risk organs were allocated to recipients with worse waiting list position. There was no relation between DRI and MELD score. Afrodescendents and elderly donor organs were allocated to lower MELD score and worse waiting list position recipients. CONCLUSION: There is no relation between DRI and MELD on liver allocation. However, DRI interferes with allocation decision based on recipients waiting list position. Donor race and age interfere on both recipient MELD score and waiting list position
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spelling pubmed-73575532020-07-21 RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT de FREITAS, Alexandre Coutinho Teixeira COELHO, Júlio Cezar Uili WATANABE, Manoelle Risnei LIMA, Rachel Lins das Chagas Arq Bras Cir Dig Original Article BACKGROUND: Tools such as MELD score and DRI are currently used to predict risks and benefits on liver allocation for transplantation. AIM: To evaluate the relation between donor quality and recipient severity on liver allocation. METHODS: Liver transplants performed in 2017 and 2018 were evaluated. Data were collected from Paraná’s State Government Registry. DRI was evaluated in relation to recipient MELD score and position on waiting list. RESULTS: It was observed relation between DRI and position on waiting list: higher risk organs were allocated to recipients with worse waiting list position. There was no relation between DRI and MELD score. Afrodescendents and elderly donor organs were allocated to lower MELD score and worse waiting list position recipients. CONCLUSION: There is no relation between DRI and MELD on liver allocation. However, DRI interferes with allocation decision based on recipients waiting list position. Donor race and age interfere on both recipient MELD score and waiting list position Colégio Brasileiro de Cirurgia Digestiva 2020-07-08 /pmc/articles/PMC7357553/ /pubmed/32667529 http://dx.doi.org/10.1590/0102-672020190001e1499 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
de FREITAS, Alexandre Coutinho Teixeira
COELHO, Júlio Cezar Uili
WATANABE, Manoelle Risnei
LIMA, Rachel Lins das Chagas
RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT
title RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT
title_full RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT
title_fullStr RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT
title_full_unstemmed RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT
title_short RELATIONSHIP BETWEEN DONOR QUALITY AND RECIPIENT GRAVITY IN LIVER TRANSPLANT
title_sort relationship between donor quality and recipient gravity in liver transplant
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357553/
https://www.ncbi.nlm.nih.gov/pubmed/32667529
http://dx.doi.org/10.1590/0102-672020190001e1499
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