Effect of sodium (S)-2-hydroxyglutarate in male, and succinic acid in female Wistar rats against renal ischemia-reperfusion injury, suggesting a role of the HIF-1 pathway

BACKGROUND: Ischemia–reperfusion (IR) injury is the main cause of delayed graft function in solid organ transplantation. Hypoxia-inducible factors (HIFs) control the expression of genes related to preconditioning against IR injury. During normoxia, HIF-α subunits are marked for degradation by the eg...

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Detalles Bibliográficos
Autores principales: Cienfuegos-Pecina, Eduardo, Ibarra-Rivera, Tannya R., Saucedo, Alma L., Ramírez-Martínez, Luis A., Esquivel-Figueroa, Deanna, Domínguez-Vázquez, Ixel, Alcántara-Solano, Karina J., Moreno-Peña, Diana P., Alarcon-Galvan, Gabriela, Rodríguez-Rodríguez, Diana Raquel, Torres-González, Liliana, Muñoz-Espinosa, Linda E., Pérez-Rodríguez, Edelmiro, Cordero-Pérez, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357568/
https://www.ncbi.nlm.nih.gov/pubmed/32728491
http://dx.doi.org/10.7717/peerj.9438

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