High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients

Despite development of markers for identification of cancer stem cells, the mechanism underlying the survival and division of cancer stem cells in breast cancer remains unclear. Here we report that PKCλ expression was enriched in basal-like breast cancer, among breast cancer subtypes, and was correl...

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Detalles Bibliográficos
Autores principales: Nozaki, Yuka, Motomura, Hitomi, Tamori, Shoma, Kimura, Yumiko, Onaga, Chotaro, Kanai, Shotaro, Ishihara, Yuka, Ozaki, Ayaka, Hara, Yasushi, Harada, Yohsuke, Mano, Yasunari, Sato, Tsugumichi, Sato, Keiko, Sasaki, Kazunori, Ishiguro, Hitoshi, Ohno, Shigeo, Akimoto, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357771/
https://www.ncbi.nlm.nih.gov/pubmed/32658903
http://dx.doi.org/10.1371/journal.pone.0235747

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