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Cardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains

BACKGROUND: The mouse model of transverse aortic constriction (TAC) has been widely used as a cardiac stress in the investigation of the molecular mechanisms of cardiac hypertrophy. Recently, the International Knockout Mouse Consortium has selected the C57BL/6NTac (BL/6N) mouse strain to generate nu...

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Detalles Bibliográficos
Autores principales: Zi, Min, Stafford, Nicholas, Prehar, Sukhpal, Baudoin, Florence, Oceandy, Delvac, Wang, Xin, Bui, Thuy, Shaheen, Mohamed, Neyses, Ludwig, Cartwright, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357793/
https://www.ncbi.nlm.nih.gov/pubmed/32699840
http://dx.doi.org/10.1016/j.crphys.2019.10.001