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Usefulness of FRAIL Scale in Heart Valve Diseases
BACKGROUND: The frailty syndrome is a serious health problem for an aging population. The occurrence of frailty in the group of symptomatic patients undergoing heart valve surgery may have additional clinical implications. The predictive ability of the FRAIL scale in patients undergoing heart valve...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358089/ https://www.ncbi.nlm.nih.gov/pubmed/32753858 http://dx.doi.org/10.2147/CIA.S239054 |
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author | Duchnowski, Piotr Szymański, Piotr Kuśmierczyk, Mariusz Hryniewiecki, Tomasz |
author_facet | Duchnowski, Piotr Szymański, Piotr Kuśmierczyk, Mariusz Hryniewiecki, Tomasz |
author_sort | Duchnowski, Piotr |
collection | PubMed |
description | BACKGROUND: The frailty syndrome is a serious health problem for an aging population. The occurrence of frailty in the group of symptomatic patients undergoing heart valve surgery may have additional clinical implications. The predictive ability of the FRAIL scale in patients undergoing heart valve surgery during a 30-day follow-up has not yet been described. PATIENTS AND METHODS: A prospective study was conducted on a group of consecutive patients with hemodynamically significant valve disease (aortic stenosis, aortic regurgitation, mitral stenosis and mitral regurgitation) that underwent elective valve surgery in 2014–2019. The primary endpoint was 30-day mortality. Univariate analysis, followed by multivariate regression analysis, was performed. RESULTS: The study group included 672 consecutive patients (aortic valve stenosis, aortic regurgitation, mitral stenosis and mitral regurgitation) who underwent replacement or repair of the valve. Twenty-five patients died during the 30-day follow-up. At multivariate analysis, FRAIL scale result (OR 2.802; 95% CI 1.275–6.157; p=0.01) and red cell distribution width (RDW) (OR 1.810; 95% CI 1.181–2.775; p=0.006) remained independent predictors of the primary endpoint. CONCLUSION: The presented study showed the predictive ability of the FRAIL scale result in patients undergoing heart valve surgery for 30-day mortality. |
format | Online Article Text |
id | pubmed-7358089 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-73580892020-08-03 Usefulness of FRAIL Scale in Heart Valve Diseases Duchnowski, Piotr Szymański, Piotr Kuśmierczyk, Mariusz Hryniewiecki, Tomasz Clin Interv Aging Original Research BACKGROUND: The frailty syndrome is a serious health problem for an aging population. The occurrence of frailty in the group of symptomatic patients undergoing heart valve surgery may have additional clinical implications. The predictive ability of the FRAIL scale in patients undergoing heart valve surgery during a 30-day follow-up has not yet been described. PATIENTS AND METHODS: A prospective study was conducted on a group of consecutive patients with hemodynamically significant valve disease (aortic stenosis, aortic regurgitation, mitral stenosis and mitral regurgitation) that underwent elective valve surgery in 2014–2019. The primary endpoint was 30-day mortality. Univariate analysis, followed by multivariate regression analysis, was performed. RESULTS: The study group included 672 consecutive patients (aortic valve stenosis, aortic regurgitation, mitral stenosis and mitral regurgitation) who underwent replacement or repair of the valve. Twenty-five patients died during the 30-day follow-up. At multivariate analysis, FRAIL scale result (OR 2.802; 95% CI 1.275–6.157; p=0.01) and red cell distribution width (RDW) (OR 1.810; 95% CI 1.181–2.775; p=0.006) remained independent predictors of the primary endpoint. CONCLUSION: The presented study showed the predictive ability of the FRAIL scale result in patients undergoing heart valve surgery for 30-day mortality. Dove 2020-07-09 /pmc/articles/PMC7358089/ /pubmed/32753858 http://dx.doi.org/10.2147/CIA.S239054 Text en © 2020 Duchnowski et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Duchnowski, Piotr Szymański, Piotr Kuśmierczyk, Mariusz Hryniewiecki, Tomasz Usefulness of FRAIL Scale in Heart Valve Diseases |
title | Usefulness of FRAIL Scale in Heart Valve Diseases |
title_full | Usefulness of FRAIL Scale in Heart Valve Diseases |
title_fullStr | Usefulness of FRAIL Scale in Heart Valve Diseases |
title_full_unstemmed | Usefulness of FRAIL Scale in Heart Valve Diseases |
title_short | Usefulness of FRAIL Scale in Heart Valve Diseases |
title_sort | usefulness of frail scale in heart valve diseases |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358089/ https://www.ncbi.nlm.nih.gov/pubmed/32753858 http://dx.doi.org/10.2147/CIA.S239054 |
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