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Regulation of Nrf2/Keap1 signalling in human skeletal muscle during exercise to exhaustion in normoxia, severe acute hypoxia and post-exercise ischaemia: Influence of metabolite accumulation and oxygenation

The Nrf2 transcription factor is induced by reactive oxygen and nitrogen species and is necessary for the adaptive response to exercise in mice. It remains unknown whether Nrf2 signalling is activated by exercise in human skeletal muscle. Here we show that Nrf2 signalling is activated by exercise to...

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Detalles Bibliográficos
Autores principales: Gallego-Selles, Angel, Martin-Rincon, Marcos, Martinez-Canton, Miriam, Perez-Valera, Mario, Martín-Rodríguez, Saúl, Gelabert-Rebato, Miriam, Santana, Alfredo, Morales-Alamo, David, Dorado, Cecilia, Calbet, Jose A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358388/
https://www.ncbi.nlm.nih.gov/pubmed/32863217
http://dx.doi.org/10.1016/j.redox.2020.101627

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