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Glucose Induces IL-1α-Dependent Inflammation and Extracellular Matrix Proteins Expression and Deposition in Renal Tubular Epithelial Cells in Diabetic Kidney Disease

Diabetes mellitus is linked with metabolic stress that induces cellular damage and can provoke renal inflammation and fibrotic responses that eventually lead to chronic kidney disease. Because the inflammasome, interleukin 1 (IL-1), IL-1α/IL-β, and IL-1R are central elements of kidney inflammation a...

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Detalles Bibliográficos
Autores principales:	Salti, Talal, Khazim, Khaled, Haddad, Rami, Campisi-Pinto, Salvatore, Bar-Sela, Gil, Cohen, Idan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358427/ https://www.ncbi.nlm.nih.gov/pubmed/32733443 http://dx.doi.org/10.3389/fimmu.2020.01270

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