Cargando…

Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy

Background: Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America. Thirty percent of infected individuals develop chronic Chagas cardiomyopathy (CCC), an inflammatory dilated cardiomyopathy that is the most important clinical consequence of T. cruzi infection, while...

Descripción completa

Detalles Bibliográficos
Autores principales:	Frade-Barros, Amanda Farage, Ianni, Barbara Maria, Cabantous, Sandrine, Pissetti, Cristina Wide, Saba, Bruno, Lin-Wang, Hui Tzu, Buck, Paula, Marin-Neto, José Antonio, Schmidt, André, Dias, Fabrício, Hirata, Mario Hiroyuki, Sampaio, Marcelo, Fragata, Abílio, Pereira, Alexandre Costa, Donadi, Eduardo, Rodrigues, Virmondes, Kalil, Jorge, Chevillard, Christophe, Cunha-Neto, Edecio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358543/ https://www.ncbi.nlm.nih.gov/pubmed/32733459 http://dx.doi.org/10.3389/fimmu.2020.01386

Ejemplares similares

Corrigendum: Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy
por: Farage Frade-Barros, Amanda, et al.
Publicado: (2020)

Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways
por: Frade, Amanda Farage, et al.
Publicado: (2013)

Polymorphism in the Alpha Cardiac Muscle Actin 1 Gene Is Associated to Susceptibility to Chronic Inflammatory Cardiomyopathy
por: Frade, Amanda Farage, et al.
Publicado: (2013)

Myocardial Chemokine Expression and Intensity of Myocarditis in Chagas Cardiomyopathy Are Controlled by Polymorphisms in CXCL9 and CXCL10
por: Nogueira, Luciana Gabriel, et al.
Publicado: (2012)

Blood DNA methylation marks discriminate Chagas cardiomyopathy disease clinical forms
por: Brochet, Pauline, et al.
Publicado: (2022)

Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy
por: Brochet, Pauline, et al.
Publicado: (2022)

Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy
por: Chevillard, Christophe, et al.
Publicado: (2018)

Chagas Disease Cardiomyopathy: Immunopathology and Genetics
por: Cunha-Neto, Edecio, et al.
Publicado: (2014)

Whole-Genome Cardiac DNA Methylation Fingerprint and Gene Expression Analysis Provide New Insights in the Pathogenesis of Chronic Chagas Disease Cardiomyopathy
por: Laugier, Laurie, et al.
Publicado: (2017)

miRNAs may play a major role in the control of gene expression in key pathobiological processes in Chagas disease cardiomyopathy
por: Laugier, Laurie, et al.
Publicado: (2020)

Evidence for T Cell Help in the IgG Response against Tandemly Repetitive Trypanosoma cruzi B13 Protein in Chronic Chagas Disease Patients
por: Duranti, Marcia, et al.
Publicado: (2012)

Matrix Metalloproteinase 2 and 9 Enzymatic Activities are Selectively Increased in the Myocardium of Chronic Chagas Disease Cardiomyopathy Patients: Role of TIMPs
por: Baron, Monique Andrade, et al.
Publicado: (2022)

Polymorphic Sites at the Immunoregulatory CTLA-4 Gene Are Associated with Chronic Chagas Disease and Its Clinical Manifestations
por: Dias, Fabrício C., et al.
Publicado: (2013)

A Doença de Chagas: Seria o Barbeiro o Único Culpado?
por: Fragata, Abilio Augusto
Publicado: (2021)

Rare Pathogenic Variants in Mitochondrial and Inflammation-Associated Genes May Lead to Inflammatory Cardiomyopathy in Chagas Disease
por: Ouarhache, Maryem, et al.
Publicado: (2021)

ChagasDB: 80 years of publicly available data on the molecular host response to Trypanosoma cruzi infection in a single database
por: Brochet, Pauline, et al.
Publicado: (2023)

Impairment of Multiple Mitochondrial Energy Metabolism Pathways in the Heart of Chagas Disease Cardiomyopathy Patients
por: Teixeira, Priscila Camillo, et al.
Publicado: (2021)

Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects
por: Deng, Xutao, et al.
Publicado: (2013)

Selective Decrease of Components of the Creatine Kinase System and ATP Synthase Complex in Chronic Chagas Disease Cardiomyopathy
por: Teixeira, Priscila Camillo, et al.
Publicado: (2011)

Evaluation of Parasiticide Treatment with Benznidazol in the Electrocardiographic, Clinical, and Serological Evolution of Chagas Disease
por: Fragata-Filho, Abilio Augusto, et al.
Publicado: (2016)

Ebi3 Prevents Trypanosoma cruzi-Induced Myocarditis by Dampening IFN-γ-Driven Inflammation
por: Medina, Tiago Silva, et al.
Publicado: (2017)

The effect of beta-blockade on myocardial remodelling in Chagas' cardiomyopathy
por: de Souza Pimentel, Walace, et al.
Publicado: (2012)

Effect of mild aerobic training on the myocardium of mice with chronic Chagas disease
por: Preto, Emerson, et al.
Publicado: (2015)

Immunology and Infection by Protozoan Parasites
por: Cunha-Neto, Edecio, et al.
Publicado: (2015)

Mitochondria as a Cellular Hub in Infection and Inflammation
por: Andrieux, Pauline, et al.
Publicado: (2021)

Myocardial Gene Expression of T-bet, GATA-3, Ror-γt, FoxP3, and Hallmark Cytokines in Chronic Chagas Disease Cardiomyopathy: An Essentially Unopposed T(H)1-Type Response
por: Nogueira, Luciana Gabriel, et al.
Publicado: (2014)

Genetic and Functional Role of TNF-alpha in the Development Trypanosoma cruzi Infection
por: Pissetti, Cristina Wide, et al.
Publicado: (2011)

Editorial: Mitochondria at the Crossroads of Immunity and Inflammatory Tissue Damage
por: Nunes, João Paulo Silva, et al.
Publicado: (2021)

Parasitic Load Correlates With Left Ventricular Dysfunction in Patients With Chronic Chagas Cardiomyopathy
por: de Oliveira, Maykon Tavares, et al.
Publicado: (2021)

Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection
por: Ferreira, Ludmila Rodrigues Pinto, et al.
Publicado: (2017)

Chagas Disease Megaesophagus Patients Carrying Variant MRPS18B P260A Display Nitro-Oxidative Stress and Mitochondrial Dysfunction in Response to IFN-γ Stimulus
por: Silva, Karla Deysiree Alcântara, et al.
Publicado: (2022)

Baroreflex Sensitivity and its Association with Arrhythmic Events in Chagas Disease
por: Santos, Astrid Meireles, et al.
Publicado: (2014)

New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response
por: Madeira, Rafael Pedro, et al.
Publicado: (2021)

Galectina-3 Associada a Formas Graves e Mortalidade em Longo Prazo em Pacientes com Doença de Chagas
por: Fernandes, Fábio, et al.
Publicado: (2021)

Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy
por: Nunes, João Paulo Silva, et al.
Publicado: (2021)

Detection of myocardial inflammation in Chagas' disease by cardiac magnetic resonance
por: Torreão, Jorge A, et al.
Publicado: (2013)

Anti-Trypanosoma cruzi antibody profiling in patients with Chagas disease treated with benznidazole assessed by genome phage display
por: Rodriguez Carnero, Luis Antonio, et al.
Publicado: (2023)

Association of Interferon-Gamma Gene Polymorphism (+874 T/A) with Systemic Sclerosis
por: Wastowski, Isabela J., et al.
Publicado: (2009)

Local IgE in patients with allergic rhinitis
por: Rodrigues, Adriana Teixeira, et al.
Publicado: (2015)

The challenge of risk assessment in the riddle of Chagas heart disease
por: Marin-Neto, José Antonio, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ijumlsf34k39f1e05o9h56peqk