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A simple open source bioinformatic methodology for initial exploration of GPCR ligands’ agonistic/antagonistic properties

Drug development is an arduous procedure, necessitating testing the interaction of a large number of potential candidates with potential interacting (macro)molecules. Therefore, any method which could provide an initial screening of potential candidate drugs might be of interest for the acceleration...

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Detalles Bibliográficos
Autores principales: Panagiotopoulos, Athanasios A., Papachristofi, Christina, Kalyvianaki, Konstantina, Malamos, Panagiotis, Theodoropoulos, Panayiotis A., Notas, George, Calogeropoulou, Theodora, Castanas, Elias, Kampa, Marilena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358596/
https://www.ncbi.nlm.nih.gov/pubmed/32662237
http://dx.doi.org/10.1002/prp2.600