Cargando…
Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy
BACKGROUND: Fragmented QRS (fQRS) complex, with various morphology, has been recently described as a diagnostic criterion of several cardiac diseases. However, there are little data regarding the prognostic role of fQRS in peripartum cardiomyopathy (PPCM) patients. We aimed to investigate the effect...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358786/ https://www.ncbi.nlm.nih.gov/pubmed/31587432 http://dx.doi.org/10.1111/anec.12708 |
_version_ | 1783558914935095296 |
---|---|
author | Tekin Tak, Bahar Cay, Serkan Ekizler, Firdevs Aysenur Ozcan Cetin, Elif Hande Pamukcu, Hilal Erken Kafes, Habibe Ulvan, Nedret Ozeke, Ozcan Ozcan, Firat Topaloglu, Serkan Aras, Dursun |
author_facet | Tekin Tak, Bahar Cay, Serkan Ekizler, Firdevs Aysenur Ozcan Cetin, Elif Hande Pamukcu, Hilal Erken Kafes, Habibe Ulvan, Nedret Ozeke, Ozcan Ozcan, Firat Topaloglu, Serkan Aras, Dursun |
author_sort | Tekin Tak, Bahar |
collection | PubMed |
description | BACKGROUND: Fragmented QRS (fQRS) complex, with various morphology, has been recently described as a diagnostic criterion of several cardiac diseases. However, there are little data regarding the prognostic role of fQRS in peripartum cardiomyopathy (PPCM) patients. We aimed to investigate the effect of fQRS on predicting left ventricular (LV) nonrecovery in patients with peripartum cardiomyopathy (PPCM). METHODS: Ninety patients (mean age: 34.7 ± 6.5 years) with the diagnosis of PPCM were analyzed retrospectively. The median follow‐up period of was 67.0 (12.0–192.0) months. Fragmented QRS was defined as the presence of various RSR’ patterns (QRS duration < 120 ms) with or without Q wave, which include an additional R wave (R’ prime) or notching of the R wave or S wave, or the presence of more than one R' (fragmentation) without typical bundle branch block. Recovery of LV function was defined as the presence of LV ejection fraction (EF) >45%. RESULTS: Of the patients, 54 (60%) did not recover LV function at the last follow‐up visit (nonrecovery group), while 36 of the patients (40%) exhibited LV recovery (recovery group). LV ejection fraction (EF) and fQRS were identified as independent predictors of LV nonrecovery in patients with PPCM (odds ratio OR: 5.546, 95% confidence interval CI: 0.792–0.979, p = .019 and OR: 5.986, 95% CI: 1.313–11.787, p = .014, respectively). CONCLUSION: Our data firstly indicated that presence of fQRS was a significant predictor of LV nonrecovery in patients with PPCM. The fQRS might assist in identifying high‐risk patients. |
format | Online Article Text |
id | pubmed-7358786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73587862020-07-17 Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy Tekin Tak, Bahar Cay, Serkan Ekizler, Firdevs Aysenur Ozcan Cetin, Elif Hande Pamukcu, Hilal Erken Kafes, Habibe Ulvan, Nedret Ozeke, Ozcan Ozcan, Firat Topaloglu, Serkan Aras, Dursun Ann Noninvasive Electrocardiol Original Articles BACKGROUND: Fragmented QRS (fQRS) complex, with various morphology, has been recently described as a diagnostic criterion of several cardiac diseases. However, there are little data regarding the prognostic role of fQRS in peripartum cardiomyopathy (PPCM) patients. We aimed to investigate the effect of fQRS on predicting left ventricular (LV) nonrecovery in patients with peripartum cardiomyopathy (PPCM). METHODS: Ninety patients (mean age: 34.7 ± 6.5 years) with the diagnosis of PPCM were analyzed retrospectively. The median follow‐up period of was 67.0 (12.0–192.0) months. Fragmented QRS was defined as the presence of various RSR’ patterns (QRS duration < 120 ms) with or without Q wave, which include an additional R wave (R’ prime) or notching of the R wave or S wave, or the presence of more than one R' (fragmentation) without typical bundle branch block. Recovery of LV function was defined as the presence of LV ejection fraction (EF) >45%. RESULTS: Of the patients, 54 (60%) did not recover LV function at the last follow‐up visit (nonrecovery group), while 36 of the patients (40%) exhibited LV recovery (recovery group). LV ejection fraction (EF) and fQRS were identified as independent predictors of LV nonrecovery in patients with PPCM (odds ratio OR: 5.546, 95% confidence interval CI: 0.792–0.979, p = .019 and OR: 5.986, 95% CI: 1.313–11.787, p = .014, respectively). CONCLUSION: Our data firstly indicated that presence of fQRS was a significant predictor of LV nonrecovery in patients with PPCM. The fQRS might assist in identifying high‐risk patients. John Wiley and Sons Inc. 2019-10-06 /pmc/articles/PMC7358786/ /pubmed/31587432 http://dx.doi.org/10.1111/anec.12708 Text en © 2019 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals, LLC This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Tekin Tak, Bahar Cay, Serkan Ekizler, Firdevs Aysenur Ozcan Cetin, Elif Hande Pamukcu, Hilal Erken Kafes, Habibe Ulvan, Nedret Ozeke, Ozcan Ozcan, Firat Topaloglu, Serkan Aras, Dursun Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy |
title | Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy |
title_full | Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy |
title_fullStr | Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy |
title_full_unstemmed | Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy |
title_short | Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy |
title_sort | fragmented qrs as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358786/ https://www.ncbi.nlm.nih.gov/pubmed/31587432 http://dx.doi.org/10.1111/anec.12708 |
work_keys_str_mv | AT tekintakbahar fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT cayserkan fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT ekizlerfirdevsaysenur fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT ozcancetinelifhande fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT pamukcuhilalerken fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT kafeshabibe fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT ulvannedret fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT ozekeozcan fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT ozcanfirat fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT topalogluserkan fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy AT arasdursun fragmentedqrsasacandidatemarkerforleftventricularnonrecoveryinpatientswithperipartumcardiomyopathy |