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Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P‐wave duration and notched P wave

BACKGROUND: The mechanisms involved in changes in P wave following catheter ablation for atrial fibrillation (AF) are uncertain. This study aimed to assess the relationship between changes in P‐wave morphology and pulmonary vein (PV) reconnection following ablation by the assessment of 12‐lead surfa...

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Autores principales: Yanagisawa, Satoshi, Inden, Yasuya, Okamoto, Hiroya, Fujii, Aya, Sakamoto, Yusuke, Mamiya, Keita, Tomomatsu, Toshiro, Shibata, Rei, Murohara, Toyoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358886/
https://www.ncbi.nlm.nih.gov/pubmed/31566884
http://dx.doi.org/10.1111/anec.12712
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author Yanagisawa, Satoshi
Inden, Yasuya
Okamoto, Hiroya
Fujii, Aya
Sakamoto, Yusuke
Mamiya, Keita
Tomomatsu, Toshiro
Shibata, Rei
Murohara, Toyoaki
author_facet Yanagisawa, Satoshi
Inden, Yasuya
Okamoto, Hiroya
Fujii, Aya
Sakamoto, Yusuke
Mamiya, Keita
Tomomatsu, Toshiro
Shibata, Rei
Murohara, Toyoaki
author_sort Yanagisawa, Satoshi
collection PubMed
description BACKGROUND: The mechanisms involved in changes in P wave following catheter ablation for atrial fibrillation (AF) are uncertain. This study aimed to assess the relationship between changes in P‐wave morphology and pulmonary vein (PV) reconnection following ablation by the assessment of 12‐lead surface electrocardiogram and signal‐averaged electrocardiogram. METHODS: This retrospective study included 115 consecutive patients with paroxysmal AF that underwent repeat ablation for recurrence following initial ablation. We investigated changes in P‐wave morphology between baseline and repeat procedure in patients with and without PV reconnection. The study also included as validation group without recurrence (n = 67) following initial ablation. RESULTS: The maximum P‐wave duration (PWD) was significantly decreased from baseline to just after the procedure in all groups. However, for the PV reconnection group (n = 100), the maximum PWD was significantly increased again at the repeat procedure. In contrast, the maximum PWD was significantly reduced between baseline and repeat procedure in the non‐PV reconnection group (n = 15). The signal‐averaged PWD was significantly decreased from baseline to repeat procedure in the non‐PV reconnection group, but, conversely, was increased in the PV reconnection group. In the non‐PV reconnection group, the disappearance of notched P wave was detected in 8 of 15 patients (53%), which was significantly higher than in other groups (p = .001). A new or delayed notched P wave was identified in the PV reconnection group only. These results were confirmed in the validation group. CONCLUSIONS: The reverse dynamics of PWD after initial shortening directly following ablation were significantly associated with PV reconnection.
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spelling pubmed-73588862020-07-17 Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P‐wave duration and notched P wave Yanagisawa, Satoshi Inden, Yasuya Okamoto, Hiroya Fujii, Aya Sakamoto, Yusuke Mamiya, Keita Tomomatsu, Toshiro Shibata, Rei Murohara, Toyoaki Ann Noninvasive Electrocardiol Original Articles BACKGROUND: The mechanisms involved in changes in P wave following catheter ablation for atrial fibrillation (AF) are uncertain. This study aimed to assess the relationship between changes in P‐wave morphology and pulmonary vein (PV) reconnection following ablation by the assessment of 12‐lead surface electrocardiogram and signal‐averaged electrocardiogram. METHODS: This retrospective study included 115 consecutive patients with paroxysmal AF that underwent repeat ablation for recurrence following initial ablation. We investigated changes in P‐wave morphology between baseline and repeat procedure in patients with and without PV reconnection. The study also included as validation group without recurrence (n = 67) following initial ablation. RESULTS: The maximum P‐wave duration (PWD) was significantly decreased from baseline to just after the procedure in all groups. However, for the PV reconnection group (n = 100), the maximum PWD was significantly increased again at the repeat procedure. In contrast, the maximum PWD was significantly reduced between baseline and repeat procedure in the non‐PV reconnection group (n = 15). The signal‐averaged PWD was significantly decreased from baseline to repeat procedure in the non‐PV reconnection group, but, conversely, was increased in the PV reconnection group. In the non‐PV reconnection group, the disappearance of notched P wave was detected in 8 of 15 patients (53%), which was significantly higher than in other groups (p = .001). A new or delayed notched P wave was identified in the PV reconnection group only. These results were confirmed in the validation group. CONCLUSIONS: The reverse dynamics of PWD after initial shortening directly following ablation were significantly associated with PV reconnection. John Wiley and Sons Inc. 2019-09-30 /pmc/articles/PMC7358886/ /pubmed/31566884 http://dx.doi.org/10.1111/anec.12712 Text en © 2019 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Yanagisawa, Satoshi
Inden, Yasuya
Okamoto, Hiroya
Fujii, Aya
Sakamoto, Yusuke
Mamiya, Keita
Tomomatsu, Toshiro
Shibata, Rei
Murohara, Toyoaki
Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P‐wave duration and notched P wave
title Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P‐wave duration and notched P wave
title_full Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P‐wave duration and notched P wave
title_fullStr Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P‐wave duration and notched P wave
title_full_unstemmed Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P‐wave duration and notched P wave
title_short Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P‐wave duration and notched P wave
title_sort electrocardiogram characteristics of p wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: significance of changes in p‐wave duration and notched p wave
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358886/
https://www.ncbi.nlm.nih.gov/pubmed/31566884
http://dx.doi.org/10.1111/anec.12712
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