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Synergy of Tumor Microenvironment Remodeling and Autophagy Inhibition to Sensitize Radiation for Bladder Cancer Treatment
Tumor hypoxia, acidosis, and excessive reactive oxygen species (ROS) were the main characteristics of the bladder tumor microenvironment (TME), and abnormal TME led to autophagy activation, which facilitated cancer cell proliferation. The therapeutic efficacy of autophagy inhibitors might also be im...
Autores principales: | Lin, Tingsheng, Zhang, Qing, Yuan, Ahu, Wang, Baojun, Zhang, Feifei, Ding, Yuanzhen, Cao, Wenmin, Chen, Wei, Guo, Hongqian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359086/ https://www.ncbi.nlm.nih.gov/pubmed/32685013 http://dx.doi.org/10.7150/thno.45358 |
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