Nanotherapy delivery of c-myc inhibitor targets Protumor Macrophages and preserves Antitumor Macrophages in Breast Cancer

Tumor-associated macrophages (TAMs) enhance tumor growth in mice and are correlated with a worse prognosis for breast cancer patients. While early therapies sought to deplete all macrophages, current therapeutics aim to reprogram pro-tumor macrophages (M2) and preserve those necessary for anti-tumor...

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Detalles Bibliográficos
Autores principales: Esser, Alison K., Ross, Michael H., Fontana, Francesca, Su, Xinming, Gabay, Ariel, Fox, Gregory C., Xu, Yalin, Xiang, Jingyu, Schmieder, Anne H., Yang, Xiaoxia, Cui, Grace, Scott, Michael, Achilefu, Samuel, Chauhan, Jay, Fletcher, Steven, Lanza, Gregory M., Weilbaecher, Katherine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359087/
https://www.ncbi.nlm.nih.gov/pubmed/32685002
http://dx.doi.org/10.7150/thno.44523

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