Melatonin ameliorates necrotizing enterocolitis by preventing Th17/Treg imbalance through activation of the AMPK/SIRT1 pathway

Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease affecting premature infants. Mounting evidence supports the therapeutic effect of melatonin on NEC, although the underlying mechanisms remain unclear. Methods: NEC was induced in 10-day-old C57BL/6 pups via hypoxia and gavage feedi...

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Detalles Bibliográficos
Autores principales: Ma, Fei, Hao, Hu, Gao, Xiaoyan, Cai, Yao, Zhou, Jialiang, Liang, Puping, Lv, Junjian, He, Qiuming, Shi, Congcong, Hu, Dandan, Chen, Bowei, Zhu, Lixin, Xiao, Xin, Li, Sitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359097/
https://www.ncbi.nlm.nih.gov/pubmed/32685016
http://dx.doi.org/10.7150/thno.45862

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