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Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organization in stress-induced senescence of MSCs

BACKGROUND: Stem cell senescence has been proposed as one of the major drivers of aging, and MSC senescence contributes to aging-related diseases. Activation of mTORC1 pathway and heterochromatin organization have been characterized as two characteristics of senescent cells; however, whether mTORC1...

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Detalles Bibliográficos
Autores principales:	Liu, Hailong, Huang, Biao, Xue, Shaolong, U, Kin Pong, Tsang, Lai Ling, Zhang, Xiaohu, Li, Gang, Jiang, Xiaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359252/ https://www.ncbi.nlm.nih.gov/pubmed/32660632 http://dx.doi.org/10.1186/s13287-020-01798-1

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