Perillyle alcohol and Quercetin ameliorate monocrotaline-induced pulmonary artery hypertension in rats through PARP1-mediated miR-204 down-regulation and its downstream pathway

BACKGROUND: Pulmonary artery hypertension (PAH) is a vascular disease in the lung characterized by elevated pulmonary arterial pressure (PAP). Many miRNAs play a role in the pathophysiology of PAH. Perillyle alcohol (PA) and Quercetin (QS) are plant derivatives with antioxidant and anti-proliferativ...

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Detalles Bibliográficos
Autores principales: Rajabi, Soodeh, Najafipour, Hamid, Jafarinejad Farsangi, Saeideh, Joukar, Siyavash, Beik, Ahmad, Iranpour, Maryam, Kordestani, Zeinab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359282/
https://www.ncbi.nlm.nih.gov/pubmed/32660602
http://dx.doi.org/10.1186/s12906-020-03015-1

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