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Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription

Sperm contributes genetic and epigenetic information to the embryo to efficiently support development. However, the mechanism underlying such developmental competence remains elusive. Here, we investigated whether all sperm cells have a common epigenetic configuration that primes transcriptional pro...

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Detalles Bibliográficos
Autores principales: Oikawa, Mami, Simeone, Angela, Hormanseder, Eva, Teperek, Marta, Gaggioli, Vincent, O’Doherty, Alan, Falk, Emma, Sporniak, Matthieu, D’Santos, Clive, Franklin, Valar Nila Roamio, Kishore, Kamal, Bradshaw, Charles R., Keane, Declan, Freour, Thomas, David, Laurent, Grzybowski, Adrian T., Ruthenburg, Alexander J., Gurdon, John, Jullien, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359334/
https://www.ncbi.nlm.nih.gov/pubmed/32661239
http://dx.doi.org/10.1038/s41467-020-17238-w