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Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription
Sperm contributes genetic and epigenetic information to the embryo to efficiently support development. However, the mechanism underlying such developmental competence remains elusive. Here, we investigated whether all sperm cells have a common epigenetic configuration that primes transcriptional pro...
Autores principales: | Oikawa, Mami, Simeone, Angela, Hormanseder, Eva, Teperek, Marta, Gaggioli, Vincent, O’Doherty, Alan, Falk, Emma, Sporniak, Matthieu, D’Santos, Clive, Franklin, Valar Nila Roamio, Kishore, Kamal, Bradshaw, Charles R., Keane, Declan, Freour, Thomas, David, Laurent, Grzybowski, Adrian T., Ruthenburg, Alexander J., Gurdon, John, Jullien, Jerome |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359334/ https://www.ncbi.nlm.nih.gov/pubmed/32661239 http://dx.doi.org/10.1038/s41467-020-17238-w |
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