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Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy

Theranostics is a fast-growing field due to demands for new, efficient therapeutics which could be precisely delivered to the target site using multimodal imaging with enhancing auxiliary actions. In this review article we discuss theranostic nanoplatforms containing polymers and magnetic nanopartic...

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Detalles Bibliográficos
Autores principales: Gauger, Andrew J., Hershberger, Kian K., Bronstein, Lyudmila M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359411/
https://www.ncbi.nlm.nih.gov/pubmed/32733850
http://dx.doi.org/10.3389/fchem.2020.00561
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author Gauger, Andrew J.
Hershberger, Kian K.
Bronstein, Lyudmila M.
author_facet Gauger, Andrew J.
Hershberger, Kian K.
Bronstein, Lyudmila M.
author_sort Gauger, Andrew J.
collection PubMed
description Theranostics is a fast-growing field due to demands for new, efficient therapeutics which could be precisely delivered to the target site using multimodal imaging with enhancing auxiliary actions. In this review article we discuss theranostic nanoplatforms containing polymers and magnetic nanoparticles along with other components. Magnetic nanoparticles allow for both diagnostic and therapeutic (hyperthermia) capabilities, while polymers can be reservoirs for drugs and are easily functionalized for cell targeting. We focus on the most important design strategies to achieve optimal theranostic effects as well as the roles of different components included in theranostics, reviewing the literature from the last 5 years.
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spelling pubmed-73594112020-07-29 Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy Gauger, Andrew J. Hershberger, Kian K. Bronstein, Lyudmila M. Front Chem Chemistry Theranostics is a fast-growing field due to demands for new, efficient therapeutics which could be precisely delivered to the target site using multimodal imaging with enhancing auxiliary actions. In this review article we discuss theranostic nanoplatforms containing polymers and magnetic nanoparticles along with other components. Magnetic nanoparticles allow for both diagnostic and therapeutic (hyperthermia) capabilities, while polymers can be reservoirs for drugs and are easily functionalized for cell targeting. We focus on the most important design strategies to achieve optimal theranostic effects as well as the roles of different components included in theranostics, reviewing the literature from the last 5 years. Frontiers Media S.A. 2020-07-07 /pmc/articles/PMC7359411/ /pubmed/32733850 http://dx.doi.org/10.3389/fchem.2020.00561 Text en Copyright © 2020 Gauger, Hershberger and Bronstein. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Gauger, Andrew J.
Hershberger, Kian K.
Bronstein, Lyudmila M.
Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy
title Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy
title_full Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy
title_fullStr Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy
title_full_unstemmed Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy
title_short Theranostics Based on Magnetic Nanoparticles and Polymers: Intelligent Design for Efficient Diagnostics and Therapy
title_sort theranostics based on magnetic nanoparticles and polymers: intelligent design for efficient diagnostics and therapy
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359411/
https://www.ncbi.nlm.nih.gov/pubmed/32733850
http://dx.doi.org/10.3389/fchem.2020.00561
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