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Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
BACKGROUND: DNA methylation (DNAm) age constitutes a powerful tool to assess the molecular age and overall health status of biological samples. Recently, it has been shown that tissue-specific DNAm age predictors may present superior performance compared to the pan- or multi-tissue counterparts. The...
Autores principales: | Boroni, Mariana, Zonari, Alessandra, Reis de Oliveira, Carolina, Alkatib, Kallie, Ochoa Cruz, Edgar Andres, Brace, Lear E., Lott de Carvalho, Juliana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359467/ https://www.ncbi.nlm.nih.gov/pubmed/32660606 http://dx.doi.org/10.1186/s13148-020-00899-1 |
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