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Severely ill COVID-19 patients display augmented functional properties in SARS-CoV-2-reactive CD8(+) T cells

The molecular properties of CD8(+) T cells that respond to SARS-CoV-2 infection are not fully known. Here, we report on the single-cell transcriptomes of >80,000 virus-reactive CD8(+) T cells from 39 COVID-19 patients and 10 healthy subjects. COVID-19 patients segregated into two groups based on...

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Detalles Bibliográficos
Autores principales:	Kusnadi, Anthony, Ramírez-Suástegui, Ciro, Fajardo, Vicente, Chee, Serena J, Meckiff, Benjamin J, Simon, Hayley, Pelosi, Emanuela, Seumois, Grégory, Ay, Ferhat, Vijayanand, Pandurangan, Ottensmeier, Christian H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359524/ https://www.ncbi.nlm.nih.gov/pubmed/32676602 http://dx.doi.org/10.1101/2020.07.09.194027

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